Sticky Blood-Hughes Syndrome Support
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A strange immune anomaly

I have just been diagnosed with Hughes Syndrome in the last 2 months. I am 48 yo. Have many of the general symptoms so I won't go into detail here, but it occurred to me as I laid in the hospital for the last 25 out of 30 days, I wonder if that Rubella Titer is due to this.

Everytime for my physicals for pregnancies or work physicals they would always do a rubella (measles) titer and it would always show that I was not immune, so when I wasn't pregnant, they would give a rubella vaccine. The next year I'd have my work physical, and again, I was non immune. I even had both kinds of measles as a child. I know sometimes this disease can mess with the syphyllis test, just wondere dif anyone else had come across this anomaly with the rubella.

4 Replies

Not sure if this would cause a false negative as the APS antibodies usually cause false positives.

The rubella vaccine is known to be not so effective and this is actually a pretty common occurence in the general public from what I understand. For some reason people just don't seem to hold immunity to it.


I am taking years ago but the same happened to me with all three of my pregnancies. I was given the jab while pregnant and then after the birth was found not to be immune so given it again and this also happened for the 2 miscarriages I ended up in hospital for, Id never thought about it being conected to APLS. Nice research project for someone !!


Hi Ohiorose,

welcome to the group, we will be happy to answer any of your questions, i have an auntie who has the same issue as you she does not have APS but the vaccinne is not effective something to do with her Antibodies i will speak to her because she has not done anything diffrent but have the vacination every year.



It might be when you were first exposed to rubella (whether by vaccine or for real) your body made a mistake making the antibodies. So now when your body recognises the rubella virus/vaccine it makes the dud antibodies?

I know someone who had chicken pox 7 times - once as a child and then every time his 6 children got it - he was told this is what had happened -he was making antibodies but they were not effective ones...


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