International Congress Antiphospholipid Galveston 2011?

[Danimgw]

The International Congress Antiphospholipid Galveston 2011 recommends INR target 2-3? Is this right?

I looked everywhere on the web to find the report and you have to be in medical to download a report.

Any suggestions?

Dani

[MaryF Administrator]

Hi there - lots of expertise on here regarding INR targets from personal experience. I do not take warfarin or similar so not the right person to personally comment!

Best wishes.

Mary F

[Hidden]

Yes, they do as do the new guidelines from the British Committee for Standards in Haematology just published. I have written about it in the next newsletter Dani but they do have the caveat that every patient should be treated as an individual case and the 2-3 is just a guideline.

As you know the trick is to get the INR as low as possible (to avoid bleeds) but to be as symptom free as possible. A lot of Hughes patients do need a high INR - often between 3.0-4.5.

It will be interesting to see what next year's APLA conference says - they might do the same as the BCSH though.

Kx

[taffydaffy]

Hi all

hope your getting your 15 minutes of Vit D Its t hot for me lol

Ok my I.N.R 3.5 - 4 I can't remember how they get to this anyone with simple Info to explain it to me please x

[paddyandlin]

Hi Dani

AS number of reports from Prof Hughes as well as other Doc he suggests and INR of 3.5 . As Kate has said its very difficult to get docs to weight bleeding against symptom free.

Please do let us know how the confernce goes.

Paddy

[Manofmendip]

Hi all.

Prof Hughes told me to have a tagrget range of 3.8 - 4.2 and I feel rough if I am below about 3.3 - 3.5. I have had bouts of haematuria and some bowel bleeds but the latter was due to a polyp, it turned out.

Best wishes.

Dave

[Storky]

It just amazes me that when the man who has been credited with having had a disease named after him says that an INR should be 3-4 or at least over 3 that no one seems to be listening to him!

This is one of those times when I am glad I am on Heparin!

[kathyD64]

Hi Guys,

After serious illness age 25 with life threatening blood clots on the brain i was dx with hughes and then i had inr range of 3-4.5. However i then had a stable time on warfarin for a decade in my 30's when inrs 2-3 meant i was symptom free and kept very active with only the odd blip.

I guess as a guide inr's 2-3 will keep most people with hughes stable but certainly it can only be a guide and as kate says dosage and choices of anti coagulants need to be personlised as we all seem to be quite unique and certainly cant be treated all the same.

now, age 48 am in my second year of multiple issues related to aps and fibro but now take aspirin aswell as ? been having tia's despite inrs above 3 so currently my inr range is minimum 3.5-4. I can nolonger drink alcohol both times of late i have had a tipple (units within warfarin guidelines) my inrs have been 8.5 and currently 7.7! its crazy i take 5mg normally to achieve inr's 3-3.5 and require the odd 6mg to boost it to above 3.5.

I do wander if the longitivity of being on warfarin could now be an issue or is it just that the aps is very active at present, as have been getting odd limb issues now said to be due to vascular phenomenon - i have my consultant neurology review mon and hopefully will find out my mri brain results as my symptoms have been baffling both my rheumatologist and neurologist.

kathy xx hope everyone is having a good weekend

[Danimgw]

Thanks for all your comments. I will keep it on the safe side as I'm having extra anticoagulants I'll keep my INR on the safe side 2.5 - 3.5