I am curious how many, if any, are diagnosed with both factor V leiden and Hughes Syndrome? Is there a common "co-diagnosis"?

[PamZ]

#factorvleiden #hughessyndrome

[margaretjo]

Yes im diagnosed with both

[lucky1]

I have both

[daisyd]

I do if I am remembering right, I think their was a poll about it.

[tassie]

I have both.

Factor V Leidon is an inherited disorder Hughes is not meant to be hereditary but can occur in several members of a family.

[Lure2 in reply to tassie]

Well said Tassies. Thank you.

Kerstin

[brannanp]

I have both and have just been diagnosed with low platelets and am currently dealing with that. Both Hughes and low platelets are auto-immune and I'm trying to figure out why my immune system went haywire. Thinking more it's related to food allergies.

[Salty in reply to brannanp]

Thrombocytopenia ("low platelets") is a common manifestation of APS...it is not a separate problem

[Tranquility1]

Here are links to a few studies on Factor V Leiden and Antiphospholipid Syndrome

The combination of thrombophilic genotypes is associated with definite antiphospholipid syndrome

haematologica.org/content/8...

Risk of thrombosis in patients with antiphospholipid antibodies and factor V Leiden mutation.

ncbi.nlm.nih.gov/pubmed/100...

Antiphospholipid syndrome and factor V Leiden. Three cases with recurrent venous thrombosis.

ncbi.nlm.nih.gov/pubmed/107...

Factor V Leiden and Antiphospholipid Antibodies Are Significant Risk Factors for Ischemic Stroke in Children

stroke.ahajournals.org/cont...

Coagulopathy triggered autoimmunity: experimental antiphospholipid syndrome in factor V Leiden mice

biomedcentral.com/1741-7015...

Coexistence of factor V Leiden and primary antiphospholipid syndrome: a patient with recurrent myocardial infarctions and thrombocytopenia

link.springer.com/article/1...

[Christin]

Yes, I have both

[Tessan0221]

Yes, I have both.

[mozelle]

Hi PamZ

Yes, I was diagnosed with both 4 months ago. There is not a common diagnosis. After a history of DVT in my legs--the last time I had DVT in three deep veins in same leg, treated on warfarin for 4 mths, then was sent to a hematologist. He tested for many clotting factors, (drew 16 vials of blood)--they are 2 separate conditions--it just so happens that I tested for both. Per my doctor, Factor V Leiden is an inherited mutation of the gene, but APS is acquired, and no known cause. There are actually 2 different blood tests for both of these. I am now on warfarin for life--When were you diagnosed, and were you put on warfarin? Have other family members been tested for Factor V Leiden?