Is there anything that triggers "Catastrophic Antiphospholipid Syndrome"?

[Lhrlovesmar]

[GinaD]

I only know what I read on the Hughes site and from books on APLS. I would refer you to those.

[Tiggercat]

Yes there are definite known triggers. Two of which are cessation of warfarin or other anticoagulants without cover (bridging) and certain surgeries.

There will be others here that can also answer you, but I can speak personally about these two as my husband suffered CAPS in 2012 when they stopped his warfarin for 5 days and, due to lack of communication and bad assumptions, didn't give him cover with Clexane, and then performed abdominal surgery on him.

Thankfully he lived, but now has no adrenal glands, and suffered a permanent brain injury. He had multi organ failure at the time, but most other organs seem to have recovered.

He suffered micro occlusions, so they don't know when it happened, just that he never fully recovered from surgery. They think it happened around the time of surgery. Whether it was just the cessation of warfarin, or the surgery, or both combined, they will never know.