Public health
Research
An engaged research study to assess the effect of a ‘real-world’ dietary intervention on urinary bisphenol A (BPA) levels in teenagers
Tamara S Galloway1, Nigel Baglin2, Benjamin P Lee3, Anna L Kocur3, Maggie H Shepherd4,5, Anna M Steele4,5, BPA Schools Study Consortium6,7,8,9,10,11, Lorna W Harries3
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Abstract
Objective Bisphenol A (BPA) has been associated with adverse human health outcomes and exposure to this compound is near-ubiquitous in the Western world. We aimed to examine whether self-moderation of BPA exposure is possible by altering diet in a real-world setting.
Design An Engaged Research dietary intervention study designed, implemented and analysed by healthy teenagers from six schools and undertaken in their own homes.
Participants A total of 94 students aged between 17 and 19 years from schools in the South West of the UK provided diet diaries and urine samples for analysis.
Intervention Researcher participants designed a set of literature-informed guidelines for the reduction of dietary BPA to be followed for 7 days.
Main outcome measures Creatinine-adjusted urinary BPA levels were taken before and after the intervention. Information on packaging and food/drink ingested was used to calculate a BPA risk score for anticipated exposure. A qualitative analysis was carried out to identify themes addressing long-term sustainability of the diet.
Results BPA was detected in urine of 86% of participants at baseline at a median value of 1.22 ng/mL (IQR 1.99). No effect of the intervention diet on BPA levels was identified overall (P=0.25), but there was a positive association in those participants who showed a drop in urinary BPA concentration postintervention and their initial BPA level (P=0.003). Qualitative analysis identified themes around feelings of lifestyle restriction and the inadequacy of current labelling practices.
Conclusions We found no evidence in this self-administered intervention study that it was possible to moderate BPA exposure by diet in a real-world setting. Furthermore, our study participants indicated that they would be unlikely to sustain such a diet long term, due to the difficulty in identifying BPA-free foods.
This is an Open Access article distributed in accordance with the terms of the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original work is properly cited. See: creativecommons.org/license...
dx.doi.org/10.1136/bmjopen-... and limitations of this study
This study represents the largest assessment to date of the potential for moderating one’s own bisphenol A (BPA) exposure through diet.
The study was carried out in a ‘real-world’ setting rather than a regulated, controlled environment.
The study was carried out in teenagers, the demographic with among the highest exposure.
Qualitative analysis reveals challenges with sustaining such a diet.
Calculation of a risk score is challenging due to the pervasive nature of BPA contamination.
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bmjopen.bmj.com/content/8/2...
Lighter version from Treehugger: treehugger.com/health/study...
