B3 Nicotinomide trials….: anybody heard of the... - Glaucoma UK

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B3 Nicotinomide trials….

ChrisNorthEast profile image
13 Replies

anybody heard of the promising new Vitamin B3 Nicotinimide trials? 3grams a day in trials so far show Visual Field stabilisation apparently. Moorefields eye hospital have apparently started a 4 year trial.

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ChrisNorthEast
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JanD236 profile image
JanD236

When I had my regular check up at Moorfields recently I asked about this.

My consultant said that a trial in Australia has shown very encouraging results and therefore there’s no reason to not start taking it myself (although I’m not part of a trial).

I now take 500mg 3 times a day.

ChrisNorthEast profile image
ChrisNorthEast in reply to JanD236

Thanks Jan I’ve just seen a presentation by a Professor Jonathan Crowston. There seems to be substantial evidence as you say. I’ve ordered some too. The trial started with 1.5 g increased to 3g a day from what I’ve read. I’m meeting my consultant this afternoon so will ask him too. If taken with IOP lowering therapies it hopefully may allow us to fight this thing even better.

JanD236 profile image
JanD236 in reply to ChrisNorthEast

Thanks. Would be interesting to hear what your consultant has to say.

Welshsailor profile image
Welshsailor in reply to ChrisNorthEast

hi Chris, did you ask your consultant?

ChrisNorthEast profile image
ChrisNorthEast in reply to Welshsailor

hi there I did ask a professor of ophthalmology who advised me to take it. Initially I took 3G per day but I thought it was a bit excessive so take 1.5 g daily. Short term studies showed significant improvement in inner retinal function. Moorefields have started a 4 year trial to ascertain if this is the case over a longer term. Personal choice but I’m not waiting 4 years to find out. If it’s a viable neuro protectant then I figure why not! When you think about it, it’s only a low cost vitamin which won’t hurt so long as you don’t go silly with the dose. If I’m doubt consultst with a GP. But there is a plethora of bonafide research papers online that conclude protection is afforded by it.

Welshsailor profile image
Welshsailor in reply to ChrisNorthEast

thank you for your reply. I’ve been taking 500mg for around six months and I’ve just up’d it to 1500mg. What is your glaucoma story please?

BlueMarina profile image
BlueMarina in reply to JanD236

It sounds like a good idea, Jan. Could you tell me which one you are taking? There are many slightly different types on sale online. Nicotinamide? Niacin?

ChrisNorthEast profile image
ChrisNorthEast in reply to BlueMarina

BlueMarina it’s the same thing just different names

Hope4luck profile image
Hope4luck in reply to BlueMarina

Hi. The drug you want is Nicotinamide (also called Niacinamide). This is a derivative of Vitamin B3, which is Nicotinic acid (also called niacin). When Vitamin B3 is taken in large doses it can cause flushing but the derivative Nicotinamide does not. Hope this helps?

BlueMarina profile image
BlueMarina in reply to Hope4luck

Very clear. Thank you so much.

Redshoes15 profile image
Redshoes15

I have heard about the trial. Where are you getting the Blue Marina from? I did start taking B3 when I first heard about it so would like to get some more.

ChrisNorthEast profile image
ChrisNorthEast in reply to Redshoes15

I just by it off Amazon online

Redshoes15 profile image
Redshoes15

Thanks, I will do the same!

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