The suppression of Prolactin is required for the treatment of advanced prostate cancer

[agnut]

ncbi.nlm.nih.gov/pmc/articl...

[Lizzo30]

Larger and beer increase prolactin

Me and my husband only drink red wine

[Graham49]

Things don’t seem to have changed much since your post 6 months ago. SOC doctors are not very interested and there’s not much research. Here’s a few interesting papers since 2020:

Serum prolactin level as a predictive factor for abiraterone response in patients with metastatic castration-resistant prostate cancer

Tao Yang MD, Ying Liu MD, Shuzhen Chen MD, Jiale Tian MD, Xuyou Zhu MD, Long Zhang MD, Wei Wang MD, Yingyi Qin MD, Jens Richter PhD, Aseem Anand PhD, Chengdang Xu MD … See all authors

First published: 23 June 2022

doi.org/10.1002/pros.24402

“Conclusions

Serum PRL levels are predictive of response to AA in patients with mCRPC. Serum PRL levels are positively correlated with the volume of metastatic bone disease.”

………………………….

Circulating prolactin levels in newly diagnosed prostate cancer patients

Authors Hawar Sabah University of Sulaimani, Department of Chemistry and Biochemistry, Qlyasan New Campus, Kurdistan Region, Iraq. Dereen Najat Mohammed University of Sulaimani, Department of Chemistry and Biochemistry, Qlyasan New Campus, Kurdistan Region, Iraq.

DOI: doi.org/10.17656/jzs.10903

“Conclusions: although the majority of prostate cancer patients had normal serum prolactin levels, 22% of the study participants had hyperprolactinemia, patients with higher serum prolactin levels had high Gleason score of 9 or higher and were at stage four, indicating a possible role of higher circulating prolactin at advanced cancer stages.

…………………………….

Christopher T. Holland, Joffrey Hsu, Ameae M. Walker. S179D Prolactin Sensitizes Human PC3 Prostate Cancer Xenografts to Anti-tumor Effects of Well-Tolerated Doses of Calcitriol. Journal of Cancer Science and Clinical Therapeutics 4 (2020): 442-456.

“In conclusion, findings from this study indicate that tumors from mice receiving dual therapy showed an increase in tumor cell death with no evidence of tissue damage akin to hypervitaminosis D. Twenty eight days of dual therapy caused 50% of the tumor cells to die. A dual therapy approach may therefore be a viable option in the treatment of CRPC.”

[KocoPr]

Did i read that study correctly? The author based hos whole premise on an n=1 patient.

[Lizzo30]

The antidote to high prolactin is dopamine But if you have had ADT your testosterone may be low which can impact dopamine

One of the biggest boosters of dopamine is alcohol I have read that moderate drinking is linked to longer life for men with pca

[j-o-h-n in reply to Lizzo30]

Bottoms up........A toast to all of us = "This it for all the kisses we have snatched and vice versa"....

Good Luck, Good Health and Good Humor.

j-o-h-n

[Lizzo30 in reply to j-o-h-n]

Cheers John 😊

[j-o-h-n in reply to Lizzo30]

and Roebuck.........

Good Luck, Good Health and Good Humor.

j-o-h-n

[Mascouche in reply to Lizzo30]

The CoPilot AI advises against alcohol. I asked it how can we inhibit prolactin naturally. It's answer is as follows:

"Prolactin is a hormone produced by the pituitary gland, primarily responsible for promoting milk production during breastfeeding. If you’re looking to naturally lower prolactin levels, here are some strategies:

Reduce Alcohol Intake:

Hops in beer can stimulate prolactin production. Limit alcohol consumption, especially beer1.

Address Underlying Issues:

Check for thyroid dysfunction or undereating, as these can affect prolactin levels.

Stress Reduction:

Practice yoga, meditation, or take long, slow walks to manage stress1.

Vitamin B6:

Include foods rich in vitamin B6 (such as poultry, fish, bananas, and nuts) to support dopamine function, which inhibits prolactin release2.

Herbal Medicine:

Consider Vitex agnus-castus (chaste tree or chaste berry), which has been shown to lower prolactin levels1.

Remember to consult with a healthcare professional to tailor these approaches to your specific needs."

[Lizzo30 in reply to Mascouche]

Beer / larger is the worst drink (imo) for the prostate

Castrate resistant prostate cancer according to some scientific research feeds off prolactin

Ask AI how it feels about red wine - which is a completely different alcoholic drink to larger / beer

[Lizzo30 in reply to Mascouche]

The main antidote to prolactin is dopamine