I've been telling everyone to limit fructose for years, this study is useful. You will be healthier if you dump sugar

[nash2]

Pfizer Inc. said that results from a midstage, six-week study of its drug that prevents the body from metabolizing fructose, a natural sugar found in fruits and vegetables, showed a statistically significant improvement in liver fat.

The medication, an inhibitor of the fructokinase enzyme, could reverse or prevent the progression of the liver disease nonalcoholic steatohepatitis, known as NASH, and perhaps even treat diabetes, according to the company.

“We were pleasantly surprised by the results,” said Pfizer Senior Vice President Morris Birnbaum, who leads the New York company’s internal medicine research division. “Beyond improving liver fat, we think we’re working with a mechanism that can be used more broadly to treat metabolic abnormalities.”

bloomberg.com/news/articles...

[MolaBoggins]

Does this refer to inhibiting the metabolising of fructose used as a sweetener in processed products as well as fructose from fresh fruit? Obviously fresh fruit has added benefits of fibre, vitamins etc but as well as fructose. Also is the sweetness in root vegetables such as carrots also fructose? I love my fruit and stay away from very sweet things like mango, but will find excluding fruit very difficult (far more difficult than alcohol) now I have been diagnosed with fatty liver.

[nash2 Partner in reply to MolaBoggins]

Their goal is controlling fructose from all sources. Interesting but what happens to the fructose then? To answer your fruit question, the bowel has a limited ability to process fructose so eating it in fruit at reasonable quantities means that it never reaches the liver so that is healthier. Dose is the key. Too much too fast and you saturate the bowel so moderation.

[MolaBoggins in reply to nash2]

Many thanks for that, most comforting.