UAE for adenomyosis- pros and cons - Endometriosis UK

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UAE for adenomyosis- pros and cons

Zo95 profile image
Zo95
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Anyone had UAE for adenomyosis? If so- what’s your experience? TIA X

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Zo95
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Jmiller623 profile image
Jmiller623

UAE isn’t commonly used for adenomyosis at least here in the US. From a trusted medical source UpToDate if you’re looking for stats:

Studies on UAE for adenomyosis show a 25 percent reduction in uterine volume and clinical improvement in heavy menstrual bleeding and overall symptom reduction.

The largest study followed 264 women with adenomyosis treated with UAE, of whom 252 completed 12 months of follow-up and 195 completed five years of follow-up; median age at treatment was 38 years (range 28 to 51 years). Approximately 1.5 percent (4 of 264) had failed embolization, 3.0 percent (7 of 264) had premature ovarian insufficiency diagnosed within three months of the procedure, and there was one periprocedural death due to a pulmonary embolus. From one to five years, an additional 22 percent (57 of 264) of the cohort was lost to follow-up, nine had hysterectomies, and three died of other causes. Among the cohort that completed five years of follow-up, approximately 70 percent of women had improvement in painful and heavy menses and that improvement was greatest in women with hypervascular lesions as determined by digital subtraction angiography at the time of treatment.

ncbi.nlm.nih.gov/pmc/articl...

However, some data demonstrate high failure rates, with patients requiring additional intervention for persistent or recurrent symptoms. Pathologic examination of uteri two years after UAE has revealed viable foci of adenomyosis, which may explain these high failure rates.

pubmed.ncbi.nlm.nih.gov/156...

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