Allergic Reactions and Mass Cells

[Justdoit2015]

Hello, I have recently been diagnosed with Hypermobility EDS, via a Consultant who I was seeing for sudden non ige allergic reactions. During an hour's consultation , he explained to me that I was suffering life threatening allergic reactions, because I had been put on Beta Blockers, which lower the threshold for mass cells to activate and consequently having sudden allergic reactions. Mass Cell activation being a common comorbidly for people with EDS.

Has anyone else here experienced Mass Cell problems? Would love to discuss.

Thank you

[Aunds]

Hi Justdoit2015. I think he was talking about Mast cells and a condition called MCAD, which is not uncommon when you have EDS. It’s referred to as MCAD, mast cell activation disorder and here’s a link that might help to explain it more.

aaaai.org/conditions-treatm...

[Justdoit2015 in reply to Aunds]

Yes, thank you for your reply. That is how I understood it. Do any other members suffer from this comorbity?

[Chethams]

I have had bad reactions to many things . It’s scary . I’m going to back to immunology to be tested for MCAD . I have EDS , POTS and ME / Chronic fatigue . It took 30 years to get to the bottom of it .