Oxidants combat aging to make you live longer

This may come as a real shock to you. Free radicals - also known as oxidants produced by our bodies as we process oxygen - act on a molecular mechanism that, in other circumstances, tells a cell to kill itself!

In other words, free radicals actually promote longevity, research says.

"People believe that free radicals are damaging and cause aging but the so-called 'free radical theory of aging' is incorrect," claimed Siegfried Hekimi, a professor in at Canada-based McGill University's department of biology.

"Free radical production increases during aging because free radicals actually combat - not cause - aging. In fact, in our model organism, we can elevate free radical generation and thus induce a substantially longer life," Hekimi explained.

Programmed cell death, or apoptosis, is a process by which damaged cells commit suicide in a variety of situations: to avoid becoming cancerous, to avoid inducing auto-immune disease, or to kill off viruses that have invaded the cell.

The main molecular mechanism by which this happens is well conserved in all animals, but was first discovered in C. elegans - a discovery that resulted in a Nobel Prize.

The McGill researchers found that this same mechanism, when stimulated in the right way by free radicals, actually reinforces the cell's defenses and increases its lifespan.

It also means that apoptosis signaling can be used to stimulate mechanisms that slow down aging, researchers noted in a study published in the journal Cell.


2 Replies

  • So,what is the inference,if I may ask?

  • Normally ageing is considered to be free radical damage.

    Even diseases they say are due to free radical damage. This is where antioxidants & vitamins come into play. This is still a open-to-debate field, where there are attempts to curb the antioxidants popularity from certain sections of medical field.

    Recently one body went against usefulness of vitamins in order to crub the popularity of GNC (a hugely popular company). All perhaps because Vitamins and Antioxidants are non patentable. Its all about patents. The other day I had posted article about Nestle trying to patent fennel flower based on benefits from " दादी माँ के नुस्खे ".

    Bottom Line: It's all about PATENTS because PATENTS gets them the right to charge criminally high prices for decades. Once patent expires they come up with some other modification. This is what's happening when STATINS patent expired, when Pioz patents expired they had Janumet ready.

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