The composition of the gut flora (intestinal microbiome) is different in PD compared to healthy individuals. Lactobacillaceae is a bacterial family that is present in larger amounts in the intestines of people with PD. Interestingly, researchers have described opposite effects for Lactobacillaceae in PD. On one hand, some scientific studies have found that these gut bacteria are connected to worse movement problems and with the early breakdown of the PD medicine levodopa. On the other hand, there are studies that found that treating people with PD with probiotics containing Lactobacillaceae improved their movement and lessened their stomach and gut problems. For this article, we reviewed the various studies on this subject. We found that the effect seems to depend on the particular species of bacterium, within the wider Lactobacillaceae family. The species L. plantarum shows favorable properties in PD: fewer problems with movement and less inflammation of the bowels. The species L. brevis, L. curvatus, and L. fermentum, on the other hand, have properties that might be negative for people with PD.
February 3, 2025, Radboud UMC, The Netherlands
journals.sagepub.com/doi/10...
doi.org/10.1177/1877718X241...
According to Parkibot, the following foods predominantly contain the beneficial L. plantarum: Kimchi, Sauerkraut, Natural Yogurts, Kefir, Kombucha, Miso, and Tempeh.