opicapone and sleep

[ShakingInMyBoots1]

journals.sagepub.com/doi/fu...

Interesting study

[michelagvolpe]

I have been taking 50mg of opicapone for over a year and I have to take it in the morning because it disturbs my sleep in the evening. As for its effectiveness, if I take it 1 hour before the second dose of C/L, it starts to take effect after 30 minutes instead of 1 hour. So for me, Opicapone gives a few more minutes per day of effectiveness than C/L.

[ShakingInMyBoots1 in reply to michelagvolpe]

I don’t take it but was curious what others experience is. TY

[Windermere1]

I added Opicapone to my Madopar 6 months ago and it’s been life changing.

1 x 50 mg taken at 9.00pm extends my On time from 3/4.hours to 7 hours and I stopped one dose of Madopar

No side effects whatsoever

[00Mark]

Hi. I have been taking a bedtime dose of 50mg Opicapone for about six months. My impression is that it smoothes out the peaks and troughs of my carbidopa/levodopa levels over 24 hours.I still have occasional problems with insomnia, but less so than before. My daytime fatigue is also a little better. The only downside is that it turned my urine yellow, but I can live with that ....