Neupro side effects

[Frances24E]

Neurologist suggested adding two mg Neupro patches to regime of Zadago plus Madopar 1.5 three times a day. Diagnosed 7 years ago, first twitch 13 years ago. Only lasted one day as I had nausea, vomiting, headache, cold sweats and sleepiness. Is this normal? I have had previous similarly adverse experience with Pramepaxole, I held out for 14 days that time before stopping. Should I persevere? Is it likely to improve?

[LeharLover62]

Wow! Vomitting? That’s pretty extreme.

Hubby had nausea for a long time (off and on for years) with Neupro but never vomiting. He would use a little alka seltzer at night to calm the stomach and was fine.

That’s also a pretty low dose…IDK, maybe give it a break and try again in a few weeks?

[Parkie1]

I started on Neupro last June. It gave me awful nausea for 2 weeks. Same again stepping up to 4mg, then it stopped.The hope was that it would help with the food/meds issues due to it being transdermal, bypassing my very lazy gut, but it has increased dyskinesia, and so I'm back down to 2mg along with madopar. It does help me sleep at night, but for some people there is the danger of sudden sleep. I hope you find it to be effective, once the sickness settles down.

[estubbs79]

I tried it years ago and it gave me orthostatic Hypertension I had to cut the pieces smaller, but stopped altogether. I hardly take any medication except for. 1/4 tab cl with my mucuna

[Frances24E in reply to estubbs79]

I noticed quite a few take mucuna. Is there a reason for that?

[estubbs79 in reply to Frances24E]

less side effects than pharmaceutical medication. It comes from a natural L-dopa plant.

[veronicacoath]

Hi - my husband tried Neupro patches with his Madopar and found they worked for a while to help sleep and then had to be increased twice more from 1-4mg in just a couple of months. Not only did they not improve his sleep and movement symptoms but they actually caused severe Restless Legs Syndrome which he hadn't suffered from before!! I read the literature which confirmed that too much medication can cause 'Augmentation' i.e. it takes higher and higher doses to achieve the same result. The legs improved once he stopped. But at least he didn't get your other symptoms - just shows how different we all are. In our case the neurologist (had to go privately!) confirmed the augmentation and took him off Neupro. He now takes a low dose of Ropinerole (tablet) which is another dopamine agonist which seems to suit him better - but still no dramatic improvements! Incidentally are you in UK - if so what area? I ask because the specialists in our NHS trust (NW Kent) won't use Xadago (Saphinamide) because they 'have no experience with it' ! Yet it is very well thought of as an alternative to Rasagiline, and is reversible if there are problems,rather than having a permanent effect. Anyone else here got a view on this?

[Frances24E in reply to veronicacoath]

No Im in Australia. What annoys me is that after seeing him every 6 months for five years he has only ever done the one assessment. Hes a nice enough man but wont make conversation or explain anything. My GP refuses to refer me to anyone else as they say all neurologists are a bit strange.

[lenamm]

Neupro made me feel horrible (headache, anxiety, nausea)and caused respiratory dyskinesia for me. I stopped at after a week because my diaphragm would spasm and I felt like I couldn't breath. It did nothing to help my symptoms.

[Frances24E in reply to lenamm]

Thank you taking the time to reply. Really helps.