Published January 19, 2024:
"According to our study, frequent sleep talking (talking while asleep at least one night per week) is a risk factor for early mortality in PD. RBD with sleep talking (ST) was associated with increased mortality, while RBD without sleep talking was not. This too hints at the importance of ST."
"We think that ST could be a sign of an ongoing neurodegeneration similar to 'acting out in dreams' in RBD. We also know that disturbances of the autonomic nervous system are essential elements of PD, and, in our study, ST is associated with non-motor symptoms..."
"Sleep talkers had more non-motor symptoms compared to non-sleep talkers and a higher intake of PD medications ..."
"Although severe obesity is a risk factor for mortality, moderate overweight may be a protective factor among elderly people and in patients with neurodegenerative disease. In a large Swedish study, a reduction in mortality was seen with increased BMI up to 29.9 kg/m2 for men and 24.9 kg/m2 for women. There is also evidence that weight loss may worsen the prognosis for PD patients."