Another human study, this one shows (electrical scalp stimulation) some improvements in Early Onset PD.

[House2]

Transcranial direct current stimulation (tDCS) based non-invasive neuromodulation (applying mild battery-like electrical stimulation to the scalp), was assessed for safety and efficacy in patients suffering from Early Onset Parkinson’s Disease (EOPD). Ten idiopathic EOPD patients received tDCS at 2.0 mA (mild electrical stimulation of the scalp) for 20 min/day for 10 days within a crossover, double-blind, sham-controlled pilot study. The outcome was evaluated by measuring changes in MDS-UPDRS part III, Non-Motor Symptoms Scale (NMSS), PD-cognitive rating scale, and PD Quality of Life Questionnaire-39 scores.

The study results showed that anodal (battery-like electrical stimulation) but not sham tDCS (placebo stimulation) significantly reduced the Non-Motor Symptoms Scale scores total and "item 2" (sleep/fatigue) scores (patients with early onset Parkinson’s Disease improved with the electrical stimulation). No adverse events occurred (the treatment was safe).

M1 anodal tDCS (battery-like electrical simulation applied to the scalp located specifically over the part of the brain that controls muscle movement) might thus evoke plasticity changes (actually create beneficial chemical and structural changes to brain nerve cells/neurons) in cortical-subcortical (brain-brainstem) circuits involved in non-motor functions, supporting the value as a therapeutic option in EOPD.

pubmed.ncbi.nlm.nih.gov/381...

[park_bear]

Easier to reproduce than pulsed EMF. All that is needed is geometry and placement of the electrodes.

[House2 in reply to park_bear]

There is also a growing number of readily available stimulators. Direct current is really old technology, that is being repurposed.

[John_morris71 in reply to park_bear]

Hello park_bear

Any idea if Transcutaneous Electrical Nerve Stimulation (TENS) Device is worth trying out, especially for PD.

A few videos on You Tube indicate that they reduce stress levels and hence improvement in anxiety/depression/some rigidity via the Vagus Nerve.

[park_bear in reply to John_morris71]

I have not looked at the idea of using a TENS device to stimulate the vagus nerve so I do not know. It also might be useful to apply a TENS device in cases of dystonia, but I have not looked at that either.

[John_morris71 in reply to park_bear]

Thanks for the speedy response.

Best Wishes for a Happy New Year!!

[ParkiePerson in reply to John_morris71]

I use a TENS machine sometimes when the rigidity in my arm becomes extremely uncomfortable and it gives me significant relief.

[EnterTheDragon in reply to ParkiePerson]

I find the same results with application to my left arm. Relief of tension and stiffness.

[JJAJJ]

Although my hwp quickly passed EOPD I will give that a go ! He feels so much better when I brush his hair for ten minutes which I believe stimulates his brain and increases blood flow. My sweet young granddaughter bought him a scalp massager for Christmas 😂 she has a job for life now !

[gomelgo]

This makes sense to me since many believe that electricity is somehow disrupted in PD brains. Maybe it's like charging a battery? Same for the PoNS?