Caapi vine and the cure for Parkinson's

[Bianhua]

This looks intriguing. There is a fair amount of research and scientific articles

ayahuascah.com/the-holy-ban...

Be well to All 😇

[Boscoejean]

Pharmacology

Neurogenesis

See also: Ayahuasca § Neurogenesis; N,N-dimethyltryptamine § Neurogenesis; and psychoplastogen

Several studies have shown the alkaloids in the B. caapi vine promote neurogenesis.[7][8][9] More specifically, in vitro studies showed that harmine, tetrahydroharmine and harmaline, stimulated neural stem cell proliferation, migration, and differentiation into adult neurons.[7][9] In vivo studies conducted on the dentate gyrus of the hippocampus noted an increase in the proliferation of BrdU positive cells in response to 100 μg of 5-MeO-DMT injected intravenously in the adult mouse brain.[7]

Alkaloids

Caapi contains the following harmala alkaloids:

Harmine, 0.31–8.43%[5]

Harmaline, 0.03–0.83%[5]

Tetrahydroharmine, 0.05–2.94%[5]

These alkaloids of the beta-carboline class act as monoamine oxidase inhibitor (MAOIs). The MAOIs allow the primary psychoactive compound, DMT, which is introduced from the other common ingredient in ayahuasca Psychotria viridis, to be orally active.

The stems contain 0.11–0.83% beta-carbolines, with harmine and tetrahydroharmine as the major components.[5]

Alkaloids are present in all parts of the plant.[3]

en.wikipedia.org/wiki/Banis...

[LAJ12345]

en.wikipedia.org/wiki/Ayahu...

Ayahuasca is commonly made by the prolonged decoction of the stems of the Banisteriopsis caapi vine and the leaves of the Psychotria viridis shrub, although hundreds of species are used in addition or substitution (See "Preparation" below).[11] P. viridis contains N,N-Dimethyltryptamine (DMT), a highly psychedelic substance, although orally inactive, and B. caapi is rich on harmala alkaloids, such as harmine, harmaline and tetrahydroharmine (THH), which can act as a monoamine oxidase inhibitor (MAOi), halting liver and gastrointestinal metabolism of DMT, allowing it to reach the systemic circulation and the brain, where it activates 5-HT1A/2A/2C receptors in frontal and paralimbic areas.[12][13]

[Getz]

Any suggestion as to where to purchase this if you are in Australia?

[Bianhua in reply to Getz]

Getz hi. I don't personally know anyone who is using it yet. I am keeping and eye and researching it with naturopaths who live in the amazonia in Peru. Shall post anything interesting when I hear anything.

[WhyRBD]

You can not buy it, you have to go experience it. I am planning a 30 day trip to Peru in order to test ayahuasca on my prodromal PD (iRBD, gut dysbiosis, orthostatic hypotension, loss of smell, multiple strokes, etc) in order to document any changes. The trip includes a very cultivated diet of all local foods and 8 rounds of ayahuasca. Check with your medical team, as some it won't hurt while others will say you are nuts.

[Bianhua in reply to WhyRBD]

Although I agree that Ayahuasca is an experience and preferable to be undertaken in the Amazons, apparently there is already a processing of the the Ayahuasca or caapi vine were the hallucinogenic compound is extracted and is being used ( in tinctures as I understood it) to treat neurological issues i.e parkinsons. It is to be looked into. This would be very interesting as not everyone is be able to travel to the Amazonia. So let's watch the space.