RISE-PD Full Data Highlight IPX203’s Impa... - Cure Parkinson's

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RISE-PD Full Data Highlight IPX203’s Impact as Promising Parkinson Treatment

Farooqji profile image
6 Replies

neurologylive.com/view/rise...

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Farooqji profile image
Farooqji
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6 Replies
park_bear profile image
park_bear

extended-release carbidopa-levodopa (CD/LD)

Smittybear7 profile image
Smittybear7 in reply topark_bear

????

Esperanto profile image
Esperanto in reply topark_bear

Indeed, it seems like old wine in new bottles. Moreover, the comparison with IR CD-LD is comparing apples with oranges. One would think that a comparison with ER CD-LD would make more sense, but of course the outcome would then be somewhat less spectacular. Yet the following study shows that when comparing with Rytary, there is indeed an interesting difference, because IPX203 has a significantly longer pharmacodynamic effect.

journals.lww.com/clinicalne...

park_bear profile image
park_bear in reply toEsperanto

I hate how this company has polluted the terminology by labeling this as yet another version of ER.

That aside, more levodopa options are a good thing.

Buckholt profile image
Buckholt

Worry is that cost will be high making insurers reluctant in the US and unavailable in UK. Only useful if available

Esperanto profile image
Esperanto in reply toBuckholt

One of the few advantages of the market forces is that they must still be somewhat competitive compared to the other ER CD-LD medicines. So maybe available anyway. It would be a major improvement for intake periods longer than 5 hours.

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