Comprehensive coverage of gut health rele... - Cure Parkinson's

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Comprehensive coverage of gut health relevance and possible treatment for Parkinson

pdpatient profile image
6 Replies

I found the article titled "Diet in Parkinson's Disease: Critical Role for the Microbiome" on the NCBI website. Here's a brief overview:

**Abstract:**

The gut-brain axis and the microbiome play a pivotal role in Parkinson's Disease (PD). Diet, being a major factor that shapes the composition and function of the gut microbiome, has been postulated to be an important environmental factor that influences PD risk. This review discusses the potential role of various dietary components in PD, focusing on their effects on the gut microbiome and gut-brain axis. The potential therapeutic implications of dietary interventions in PD are also discussed.

ncbi.nlm.nih.gov/pmc/articl...

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pdpatient
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6 Replies
Bolt_Upright profile image
Bolt_Upright

That is a GREAT article! So much detail.

I clicked on the link, and it shows the article is from 2019 and these are the authors:

"Diet in Parkinson's Disease: Critical Role for the Microbiome

Aeja Jackson,1,2 Christopher B. Forsyth,1,2 Maliha Shaikh,1 Robin M. Voigt,1,2 Phillip A. Engen,1 Vivian Ramirez,1,2 and Ali Keshavarzian1,2,*

Author information Article notes Copyright and License information PMC Disclaimer

1Division of Digestive Diseases, Department of Internal Medicine, Rush University Medical Center, Chicago, IL, United States

2Graduate College of Rush University, Chicago, IL, United States

Edited by: Davide Martino, King's College London, United Kingdom

Reviewed by: Chien Tai Hong, Taipei Medical University, Taiwan; Francisco José Pan-Montojo, Ludwig Maximilian University of Munich, Germany

*Correspondence: Ali Keshavarzian ude.hsur@naizravahsek_ila

This article was submitted to Movement Disorders, a section of the journal Frontiers in Neurology"

Almost every paragraph deserves examination.

pdpatient profile image
pdpatient in reply toBolt_Upright

Thank you, Bolt for the corrections and I have corrected my commentary based on the comments.

Yes, this is a great article that raises some troubling questions for me. I have always been a great lover of dairy and I will have to stay away from blaming myself for perhaps causing the problem. I have stopped all dairy and it is miserable. Rest of the diet is manageable since I am / was lacto-vegetarian.

PDpatient

Bolt_Upright profile image
Bolt_Upright in reply topdpatient

I am an outlier, and I have not been diagnosed with PD, but I have not given up dairy.

I have no special training, just a high school degree. I am also prone to error and have poor impulse control.

I think all dairy gets lumped together when it should not. The Specific Carbohydrate Diet and Wahls both allow aged cheese. I believe fermented dairy is safe. I have cheddar cheese and sour cream.

I found this study: Intake of Fermented Dairy Products Induces a Less Pro-Inflammatory Postprandial Peripheral Blood Mononuclear Cell Gene Expression Response than Non-Fermented Dairy Products: A Randomized Controlled Cross-Over Trial: sci-hub.se/10.1002/mnfr.202...

According to this trial, fermented dairy products are less pro-inflammatory than non-fermented dairy products. They compared fermented products (cheese and sour cream) with non-fermented products (butter and whipped cream). "In this study, we have shown that intake of a high-fat meal composed of fermented dairy products, and especially cheese, has a less pro-inflammatory effect than intake of the non-fermented butter and whipped cream". It's not a slam dunk, but it is enough for me to cut out butter (which is allowed on the SCD) and keep my sour cream.

Please also see my post from a year ago: Anti-Inflammatory Diet (AID) for Parkinson's healthunlocked.com/cure-par...

In this, as in all things, I may be wrong.

Bolt.

MBAnderson profile image
MBAnderson

Excellent find.

KERRINGTON profile image
KERRINGTON

Thank you !

Pixelpixie profile image
Pixelpixie

solid read. Unfortunately, does not really address already having PD but makes assumptions that the Mediterranean diet might help (among other things). What I’ve seen is that the MIND diet is even better

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