Safinamide. Does anyone use this?

[goldiewan]

I am about to trial Safinamide. I’m in the uk and this is via the NHS. Does anyone have direct experience with this? I will give an update later!

[Aussiebeanie]

Yes. I've been taking it for about 18 months and it has reduced my 'off' times.

[goldiewan in reply to Aussiebeanie]

Thanks!

[pearlette]

I trialled it recently. By Day 4 I was struggling. By Day 5 I could not walk from the station to my clinic (a 8 minute walk took 20 minutes) due to severe rigidity of lower limbs starting at the top of my lower limb (glutes).

I thik the reason for that was not the drug itself but the faxt that I did not wean down my rasagiline for a week.

The reason I am givig you this negative report is to emphasise that it is worth checking with your specialist pharmacist attached to your movement disorder neurologist.

I am aso UK based. Normally I check the literature myself but this time I did not.

[goldiewan in reply to pearlette]

Thanks for the report. Makes sense. In my case I’ve only been using sinemet, but can’t tolerate a standard dose.

[pearlette in reply to goldiewan]

Good luck.

[16Dahlias]

my movement disorder neurologist has up my cinnamon quite a bit. I’m just wondering, what is a standard dose?:

[16Dahlias in reply to 16Dahlias]

Apologies I meant Sinimet- 8 a day seems a lot.