Honeymoon ?

[Esperanto]

It will still be night. I guess 4:30 because that's my new rhythm. Thankfully more than 4 hours of sleep again instead of the usual 2 hours from a month ago. It is pitch dark with my closed eyes still not opening by themselves. I feel my partner has already left for another room so I can wake up quietly and she can hopefully continue sleeping. My cold feet are on fire from the neuropathy, but not as violently as while walking. That could be another problem in my first powerwalk workout tomorrow. With fascination I listen to my buzzing brain, like the background noise of a city coming to life, marveling more and more at what is going on there. My whole body trembles restlessly, but the visible tremors are still at rest. It feels familiar by now. I try to observe and breathe consciously as I have just learned to do in Qi Gong and signal with pleasure that I have another morning erection. If this is not a honeymoon?

I feel happy and want to share this with you. That won't quite work with that severely affected short term memory. It forces me to maintain this state and rehearse what I experience over and over again. I consciously open my eyes while the day has started so intensely before and begin to write.

Have a wonderful day! 🍀

[park_bear]

Neuropathy can result from low levels of vitamin B6. Levodopa medications increase the need for B6 and create the need for supplementation. More details here:

healthunlocked.com/cure-par...

healthunlocked.com/cure-par...

Regarding Qigong, I abide in Chi meditation before dawn, which seems to make up for the lost sleep.

[Esperanto in reply to park_bear]

You yourself applied supplementation with vitamin B6 in combination with the C/L medication and mentioned: “Case in point, I take 100 mg of B6 as P5P….. I take C/L 25/100 2-3 times daily for a total of 50-75 mg of carbidopa daily. So I have an abundance of B6 in circulation that will never be disabled by the carbidopa.”

Since these links are from 5 years ago, I am curious about your experience with this and and further advancing insight. Especially regarding the doses and interval between intake. 🍀

[park_bear in reply to Esperanto]

I take B6 and C/L at different times - separated by at least 2 hours - so they do not interfere with one another.

[Esperanto in reply to park_bear]

And the dosage of the P5P is still about 25 to 50 mg more than the daily intake of carbidopa?

[park_bear in reply to Esperanto]

Yes.

[Esperanto]

Merci PB, my blissful state last night was indeed a result of that, despite the still-present PD. However, breaking the negative spiral seems like an awakening and I hope (know) that this discovery can be a drastic improvement for many others too. It is almost a mission to inform you, my fellow companions about this. As we have discussed before, the relationship of PD and neuropathy is not recognised by many neurologists, not to mention preventive measures that can avoid the neuropathy... But indeed, studies show that between 30% and 45% of people with Parkinson's disease suffer from some form of neuropathy. This may be related to the interaction between the B vitamins and levodopa/carbidopa. In particular, the significance of B6. The consequences of the love-hate relationship between the C/L medication and B6 appear to be far reaching. The B6 necessary for levodopa to work is broken down by the equally essential carbidopa component, resulting in insufficient dopamine formation. Moreover, too low a level of B6 (just like too high, sometimes caused by vitamin B complex supplements) is particularly harmful and can cause irreversible neuropathy. As an expert by experience, I was able to observe this myself after additional blood tests. Besides being quite deficient in all B vitamins, my B6 level was found to be almost nil! After a few days with additional supplement vitamin B6 (with the safe active P5P form), my situation had already greatly improved. Now after almost a month, I have even reduced my C/L medication by 70% and am below the level of the starting medication. Many of my typical PD symptoms have reduced or even disappeared. My neuropathy has hopefully stabilised but seems to be causing permanent damage. Of crucial importance therefore to do additional blood tests!!!! 🍀

[ddmagee1]

As time has gone by, the progression has taken a toll! I seldom have a morning erection, any more, and it has become hard to hold urine in, without having a small accident, at times. So, with the neuropathy, I guess the PD is doing it’s nasty work. My Doc does not address those type of problems with me.

[park_bear in reply to ddmagee1]

Pumpkin seed oil has been said to help relieve urinary urgency but I was never able to find any that did not quickly go rancid. So instead I add about a tabkespoon of pumpkin seeds to my morning porridge. It does seem to help. Also, Korean red ginseng seems to help with potency.

[Esperanto in reply to ddmagee1]

A small addition. Not getting a morning erection can also have a non-medical reason. For example, due to poor sleep. That also ensures that you cannot hold up your urine, which makes you sleep even worse, etc. One of the many vicious circles in which you can end up with PD. For me, it is always an alarm that action needs to be taken.