Cognitive decline and vitamins

[Gigi216]

Interesting paper I came across, thought I would share. It mentions Alzheimer’s but I think many of us are concerned about cognitive decline so I feel it’s helpful research

frontiersin.org/articles/10...

[tomandrai]

How can I buy PS128

[gaga1958 in reply to tomandrai]

i bought Neuralli probiotic which has ps128.-

benedlife.com/products/neur...

[Bolt_Upright]

"In conclusion, malnutrition and FT3 are important modifiable factors for AD progression. Thiamine has been known for protecting against the neuropathy, and TDP may be a link to explore the association among different organs metabolism function, further a potential target to understand the mechanism of cognitive decline. B vitamins supplementation, especially thiamine or its analogs, may be beneficial to prevent cognitive decline."

[Bolt_Upright in reply to Bolt_Upright]

May be time to put B1 back on the stack.

[Kevin51 in reply to Bolt_Upright]

You need to take BOTH Omega3 AND B Complex - this video worth a watch (start 35mins in if short of time, and 52mins in if you just want the punchline)

youtu.be/unguMlKkc74(Not working as expected?)

[goldengrove in reply to Kevin51]

Great talk! Thanks for posting!

[bookish in reply to Bolt_Upright]

Might have to try a bit harder to get someone to help with my below range FT3 then! Cheers

[MarionP]

So just eat more beef. In evolutionary terms we are not evolved past the hunter-gatherer phase anyway. If you're okay with eating your brother, that is. Otherwise just take a b complex everyday, every couple of days take an extra sublingual B12, and we'll be fine. At least as far as the study concerned.

[LAJ12345]

And for fatigue:

ncbi.nlm.nih.gov/pmc/articl...

“Loss of function in mitochondria, the key organelle responsible for cellular energy production, can result in the excess fatigue and other symptoms that are common complaints in almost every chronic disease. At the molecular level, a reduction in mitochondrial function occurs as a result of the following changes: (1) a loss of maintenance of the electrical and chemical transmembrane potential of the inner mitochondrial membrane, (2) alterations in the function of the electron transport chain, or (3) a reduction in the transport of critical metabolites into mitochondria. In turn, these changes result in a reduced efficiency of oxidative phosphorylation and a reduction in production of adenosine-5′-triphosphate (ATP). Several components of this system require routine replacement, and this need can be facilitated with natural supplements. Clinical trials have shown the utility of using oral replacement supplements, such as l-carnitine, alpha-lipoic acid (α-lipoic acid [1,2-dithiolane-3-pentanoic acid]), coenzyme Q10 (CoQ10 [ubiquinone]), reduced nicotinamide adenine dinucleotide (NADH), membrane phospholipids, and other supplements. Combinations of these supplements can reduce significantly the fatigue and other symptoms associated with chronic disease and can naturally restore mitochondrial function, even in long-term patients with intractable fatigue.”

[ddmagee1]

B-Complex vitamins, Daily vitamins, COQ10, Glucosamine, all help me, in maintaining energy etc.