Adipose fat derive stem cell treatment for Parkinson's

[20fatcats]

Hi. I am in New Zealand and have found a doctor who does stem cell infusions to help with Parkinson's. The stem cell are adipose fat cells. They are harvested by way of small liposuction procedure. They take 50ml .Then the stem cells are separated and then put back in intravenously via a drip in arm or back of hand. my question is has any body tried this treatment. I see there are other stem cells used like umbilical cord but this is different as its easy to get adipose stem cells from own body so no chance of rejection by own body. I would appreciate quick reply as I am needing to book this a pay now .

[20fatcats]

Also must add Mannitol is given which enables the stem cells to cross the blood brain barrier.

[kaypeeoh in reply to 20fatcats]

Can you cite where you saw that?

[danfitz]

This is s complete and utter scam. Run away from this as fast as you can.

[20fatcats in reply to danfitz]

I was given the name of a person who had it done and he spoke to me and said it had made a big difference.They live a in a town quite close to me and gave home nummer and mobile which I used to contact him. May I ask why ? thank you for your feed back

[danfitz in reply to 20fatcats]

You should report this person to law enforcement.

[kevowpd]

Don't.

[Bolt_Upright]

I'm not saying you should not run. You should Google the heck out of this doctor and clinic. How much are they charging you? Be very careful. Very, very careful.

But a quick Google search found this. It sounds like what you described?

Repeated infusion of autologous adipose tissue-derived stem cells for Parkinson's disease 2022 pubmed.ncbi.nlm.nih.gov/347...

"Abstract

Background: Mesenchymal stem cells are expected to have a therapeutic effect on progressive neurodegenerative diseases for which there is currently no fundamental treatment.

Aims of the study: The aim is to confirm that repeated infusion of autologous adipose tissue-derived stem cells (ADSCs) can be safely administered to patients with Parkinson's disease, and to investigate the effects of this as a pilot study.

Methods: Three patients with Parkinson's disease received five or six repeated infusions of ADSCs at intervals of approximately one month. Observations were based on medical examinations by a neurologist and interviews with the patient and caregivers. The severity of Parkinson's disease was assessed using the Hoehn & Yahr staging scale and Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS).

Results: No adverse events were observed during the observation period from the start of treatment to six months after the end of the last dose. MDS-UPDRS improved in all three patients.

Conclusions: Repeated administration of Autologous ADSCs for Parkinson's disease was safe and feasible. The results of this pilot study provide insight into the value of further research."

[danfitz]

i.stuff.co.nz/national/heal...

[kaypeeoh]

This the future. I have done this procedure to canine patients. I had two large labs with torn ACLs. Surgical repair at Colorado State Vet Center would be $10,000. The client said try something affordable or put them down. I'd read about collecting fat the way liposuction is done. Then filled tubes and spun the them down. The fat separated into three distinct portions. The middle layer contains the stem cells. One cc of bone marrow has one million stem cells. One cc of fat contains 100 million stem cells.

[kaypeeoh in reply to kaypeeoh]

I hit the send button accidentally. I treated both dongs once. The treatment brought them back to functional hunting dogs. CSU would have charged $10,000. This is a cheap, simple method. At my nurse's suggestion I charged the client $200 and felt like I'd cheated them.

[20fatcats in reply to kaypeeoh]

Thank you. I had it done in my knee as I had bad arthritis and no cartilage left and it was great. good result pain 90 percent gone and it is early days as it usually takes 3 months to full work. Its been 7 weeks.

[Bolt_Upright in reply to kaypeeoh]

I wish we had you as the vet when my dog had a bad knee. He eventually had to be put down

[Hidden]

I recommend seeking out info from Dave Asprey on the subject of stem cells. He does it personally.

daveasprey.com/how-adult-st...

I am not endorsing this but sharing what I found when researching for my Dad with PD

youtu.be/akDEhbYylfs(Not working as expected?)

[PEB69]

Sounds dodgy to me, and you have to book and pay now? Spend a few weeks looking into it a bit more, nothing is that urgent. Sounds like a clinic taking advantage of vulnerable people to me, if it was legit I am sure I would have heard about it already, we are in NZ too and I am on top of what is out there. Be careful. Maybe money better spent trialling medicinal cannabis if you don’t already use it, my husband gets his fromThe Cannabis Clinic in NZ who do Tele appointments are legit, he has very good effect from two of their products, high quality prescription meds and they don’t cost as much as you think. Just another option out there for symptom relief. Good luck, be careful.

[Motheroffive]

hopebio.org/Article?N=000285

the above are similar ongoing clinical trials - important to know the quality of the stemcells

[Solvang53]

heres a very informative documentary on stem cell therapy...youtube.com/watch?v=gYRcmDy...(Not working as expected?)

[Solvang53]

mel gibson tells his story about stem cell treatment for his father...amazing...youtube.com/watch?v=uUCJo1j...(Not working as expected?)

[Hidden in reply to Solvang53]

Wow, amazing. Not surprised because I’ve watched similar videos but so uplifting !

[Solvang53]

cellmedicine.com/

[Spencer53]

My hwp tried the stem cell treatment that you describe - did three sessions but did not see anything significant - save your money and wait till there are better advances in this field.

[20fatcats in reply to Spencer53]

Thank you for your reply. May I ask was it done in NZ or USA. What were his main symptoms before treatment.

[Robb48]

Stem cell treatment seems to bring a lot of emotions to the table lol, not sure why - but my understanding, from listening to experts in the field, is that it is very hit and miss, and we don't really understand why. Sometimes the results can be excellent, sometimes nothing happens. But there are different approaches to treatment technique also, for instance taking your own stem cells (which will settle and stay) vs using e.g. stem cells from placenta (which are all gone in a few months, but seem to poke the body into healing anyway) , and I am speaking in broad generalities rather than with specific conditions. Do the research I guess!

[kevowpd in reply to Robb48]

Scams generate a lot of emotions.

I could charge you money to shove a pineapple up your backside and having promised you that it would have a material positive impact on your PD, you'd probably feel good about it for a little while. That doesn't mean it actually did anything.

[Robb48 in reply to kevowpd]

Hah well, it's the idea that it is a a scam, that is generating your emotion, but I am not sure I agree. It is a bit of a wild west though for sure.

[kevowpd in reply to Robb48]

If there's no credibly documented evidence of a procedure's efficacy in treating PD and its safety in PWPs, its a scam.

Can you point to any currently commercially available stem cell treatments for PD that have been documented as effective and safe for PwPs?

[Robb48 in reply to kevowpd]

Can you point to any studies saying stem cell treatments dont work for Parkinsons? There are plenty of papers out there speculating on potential for neurodegenerative conditions in general. And quite a few studies using animal PD models. Plus a whole host of other studies on using them for other conditions, even injecting them into the brains of stroke victims. And my very brief search just now revealed yes, one pilot uncontrolled trial on PWP that used bone marrow stem cells, which looked promising. There may be more, I don't know. At the end of the day, there is no "accepted" treatment for PK, which is of course why we are here.

[kevowpd in reply to Robb48]

So you think it's appropriate for clinics to sell stem cell treatments without evidence of efficacy or safety simply because stem cells in general have potential?

There are stem cell trials in play and there has been a history of them with mixed success, but they are definitely not what is currently commercially available.

When a safe effective stem cell treatment for PD becomes available, it will be international news and talked about here constantly.

Edit: it's abundantly clear that you really know very little about SC4PD, which makes your contributions to multiple threads defending the sale of unproven treatments as frustrating and somewhat irresponsible.

[Robb48 in reply to kevowpd]

OK, last post before I got to bed. Your question assumes clinics are selling without evidence of safety. A questionable assumption. Which is not to say there are not potential problems. But yes, I believe in individual right to try, the problem as I can see it, is a lack of standardisation and categorisation, given that the research is ongoing and so much is not understood, with many different approaches. And you have altered what I said - I didnt say there is only general potential, I mentioned that more to back up that stem cells can have beneficial clinical effect (i.e. not a scam), but there is some reason (though perhaps weak) to believe it could help in PD. At which point, the question is one of risk and cost. I do not believe clinics should be able to operate without a good assessment of risk, nor to make claims that it would cure PD (which would fall into scam category). If that's met, go for it, personal choice. And again, the purpose of this board is to accumulate knowledge and perspective so that people can make their own decisions, given an absence of any good alternatives.

[20fatcats in reply to Robb48]

Thanks for your considered reply. Yes the clinic I am looking at don't say there is any chance I will be cured. They say that it may help with some symptom's . I'm thinking that we all have different types of the disease and suffer in many different ways so the benefits if any will vary. As I spoke to a person on the phone who had the infusion 2 years ago and said it really helped I feel like its worth considering. Surely any placebo effect would have worn off by now. I do have more questions to ask them so will wait and see.

[Parkinsonjisung]

Theres reason why these miracle cures/treatments are not well known and used by everyone.

[CPT_Helen Partner]

Please do not undertake this treatment. There is no research to show efficacy that replacing dopamine cells with fat via liposuction is a valid approach and could in fact do more harm.

[Parkinsonjisung in reply to CPT_Helen]

Should we report these when they're posted? They seem to be quite common lately

[20fatcats in reply to Parkinsonjisung]

Hi.I hope you don't report this. Didn't mean to sound like I was promoting it or saying it is good to do. I heard from a person who claims to have had it done and I was just asking for feed back to help me make a good decision. I have found this site really good for feed back and it's important we can all share from our experiences.

[Parkinsonjisung in reply to 20fatcats]

Reason I asked is because its good to get an official comment from the site on stem cell treatment like the one posted above.

[20fatcats in reply to CPT_Helen]

Hi . thank you for your reply. Just to make sure everyone knows that the stem cells are extracted out of the fat. As far as I have read and researched fat does contain stem cells and the stem cells can be separated and infused intravenously. Its not the fat that gets put back in . The problem is getting these stem cells to cross over the blood brain barrier. That's why they use Mannitol first. Hope this clarifies it all. 👍

[CPT_Helen Partner]

What is not clear is what sort of stem cells they are. Please investigate dopamine replacement cell therapy - ie replacing the stem cells that produce dopamine in the brain. Dopamine cells can be created using induced pluripotent stem cells or hESCs I have not heard of fat cells being converted to dopamine stem cells.

[kaypeeoh]

The theory is that stem cells have the potential to turn into other types of cells. That's a 'given'. The next point is a bit of a stretch. Proponents say stem cells turn into whatever type of cell is needed by the body. I saw one case where a man had severe cardiac insufficiency. He had stem cell therapy in South America. After recovery he is back to jogging and playing with his grandkids.

Ultimately this will become standard medicine. But once that happens and insurance is involved the price will sky-rocket.

[RonB1]

I believe Stem Cells are a viable treatment for the future. Parkinsons is neurodegenerative, however Stem Cells are regenerative so obviously the potential is there. Stem Cells injected directly into the brain have been shown to have a profound effect in mitigating Parkinsons symptoms. Further, I would rather have Stem Cell therapy than to do nothing and slowly wither away. P.S. How are you doing now?

[20fatcats]

Hi all who replied. update .sorry for slow response. I spent a lot of time considering it and then failed to let everyone know on this forum. I didn't go and get the stem cell treatment. I didn't feel confident. Thanks for feed back. I also decided that as my blood pressure is often dangerously low I felt that it would be too risky to have it done.