Ketamine and PD

[beehive23]

Im considering doing this for acute depression after 20grueling years of pd.

michaeljfox.org/grant/using...

[Hidden]

I have researched this a bit and am very intrigued by it. Neuro protective! Increases BDNF.

frontiersin.org/articles/10...

[beehive23 in reply to Hidden]

very interesting...cheers!

[SilentEchoes in reply to Hidden]

Works on both NMDA and AMPA receptors 😊

[Bolt_Upright]

Thanks for sharing. Good luck. I will be interested to see how it works for you.

[beehive23 in reply to Bolt_Upright]

there is no cure for life my friend...well ...almost...cheers!

[jeffmayer]

If you don't. Mind me asking have you had dbs

[beehive23 in reply to jeffmayer]

no, i refuse to have dbs.

[jeffmayer in reply to beehive23]

Don't blame you I refused aswell sounds barbaric

[dvoranel]

I am exploring Ibogaine which sounds promising as well for both depression and neuroregeneration

wayofleaf.com/psychedelics/...

[beehive23 in reply to dvoranel]

very interesting i hadnt heard of that one before...cheers!

[dvoranel in reply to beehive23]

Please do keep us posted of your experience and I will as well

[beehive23 in reply to dvoranel]

im balking just out of the gates....i have a friend using it via clinic...$600/dose...says the psychedelic effect is too much...i dont want to treat stuff by getting messed up on psychedelics....my grateful dead days are over mostly haahah...additionally after speaking to our local previously unbeknownst to me, ketamine clinic grudgingly acknowledges you will likely need boosters every 3 months in perpetuity. so it sounds like you just stay high to treat depression..i think most of us have figured that out either intuitively or by experience self medicating....and up to 18% with ptsd like symptoms may get worse...it would be cheaper to micro-dose psylocibin but again...the grateful dead effect...cheers!

[dvoranel in reply to beehive23]

For Parkinson's it is used as a microdose so you don't get the psychedelic effect - no high - just the increase in GDNF. It is used in much greater doses for other issues such as traumatic brain injury or PTSD or opioid addiction. Was your friend in the latter category?

[beehive23 in reply to dvoranel]

no just chronic depression...he indicates as a previous recreational psychedelic user that he felt uncomfortably high, after 2 doses over 2 weeks, and after calling around i found great variation between clinics as to how much how often...very little consensus...thats scarey...imo. cheers!

[beehive23 in reply to beehive23]

perfect! thanks!

[Seamus6 in reply to beehive23]

Whatever you decide, be careful!Your posts here are highly valued 👍

[dvoranel]

There is also a wealth of information on this forum regarding Ibogaine for PD - that is how I learned about it. All the best

[rebtar]

I did ketamine treatment for depression before I started C/L. The C/L cleared up residual depression/anxiety almost immediately.

I did ketamine assisted psychotherapy. This is a different approach, where a psychotherapist accompanies you during the experience, and helps to process whatever arises afterwards. It did help with my depression, but not like C/L, which tells me that dopamine deficiency was a big player.

However, it's more expensive than straight ketamine w/o psychotherapy. And not available in a lot of places.

[beehive23 in reply to rebtar]

wow thanks! so was/is it a permanent benefit for you without "boosters"?

[rebtar in reply to beehive23]

That's hard to say, since I started C/L fairly shortly afterwards, which brought my mood back to "normal".

I wouldn't hesitate to do the ketamine again though, it was a very positive experience.