Amantadine?

[septimus7]

Hello. Does anyone have experience with Amantadine? I was prescribed it but have concerns.

[20fatcats]

Hi. Yes I tried it and it made my neck feel really sore and my jaw and mouth sort of looked slightly crooked but came right as soon as i stopped it . only was on it a few days. didn't get any benefit.

[NewHope1961 in reply to 20fatcats]

Same side effects on me except for dyskinesia it’s working very well so worth the side effects

[Xenos]

Hi

Amantadine is supposed to prevent dyskinesias from C/L.

[jeffmayer]

I have been on it over a. year no problems so far

[honeycombe3]

Hi there, I have been taking Amantdine for several years. It burns my stomach but it helps with tremor. The worst side - effect is cumulative: it affects the memory and cognitive functions after a time.

[jocelyng]

I was on Gocovri (extended-release Amantadine) for several months. On the plus side. It really did knock back my tremor. Unfortunately, I had to discontinue it after the side effects kicked in. I had three: leg and arm “marbling,” swollen feet and a third one that I can’t remember. I didn’t really care about the fact that my arms and legs looked liked a kid had scribbled in red marker. I lived with the swollen feet for a while, because it was the summer. I wasn’t wearing real shoes or socks, so I had more options. By October, I realized how bad it was when my shoes were too tight to wear. I switched to Artane, and it works fine.

[Intrepid200]

When I was first diagnosed in 2011 we started out on this medication and it caused me to visit the Emergency Room as my ankle was so swollen. Please try Gocovri its same medication in a different delivery

[DianeF]

I’m taking it to treat the dyskinesia. Without it I’m a twitching mess from c/l. I would like to stop it but I’m told there’s really nothing else to address the dyskinesia.

[Parkiewife]

Hi! Here’s my two cents on Amantadine. Don’t start it! My husband has been on it for several years. At our last appointment, his doctor said to start a gradual decrease and then to stop taking it.

While it is effective with movement disorders, it’s not so good for cognitive issues. Wish we knew that earlier! Husband has started cognitive decline. Maybe D wouldn’t have this if not taking amantadine from the start!

[honeycombe3 in reply to Parkiewife]

Hi there,Ttthis is one of the first responses to this isssue over 17 years. The effects of tthe cognitive changes seem cumulative very slowly over time. I may now be at tthe point of final lifestyle choice:progressive cognitive deterioration or diskynesia. If so i shall try o remain sane and move.

Please think of all the good times so far. There may be other factors contributing to the cognitive symptoms. There may be other drugs you can try.I took Orphenadrine for 3 years before cognitive symptoms forced a change so maybe e have different tolerance s to different meds. It might be worth a try. It is no fun knowing tthe worst PD might bring. Perhaps I shal die of heart failure in my sleep. I wish! Hi

[Parkiewife in reply to Parkiewife]

Yes! My husband has been on Amantadine for 10+ years and has started cognitive decline. Gradually weaning him off, but unfortunately the damage is done.

[eschneid]

Have been on it four to five months for my mild dyskinesia and it takes care of it. I take one capsule a day at the moment 100 mg. Have not noticed any cognitive issues as of yet and don't have any major side effects from it.

[Zella23]

Husband been taking it for over a year. No side effects so far and it helps with dyskinesia.

[DianeJ in reply to Zella23]

I have been taking it in increasing doses for1 month. It’s in liquid form. Taken in 3 daily doses, through a syringe. Not convenient. Supposed to work on dyskinesia. I wanted a med to extend the time effectiveness of levodopa which it doesn’t seem to do. Hope this helps.

[S70AWD]

I've been taking amantadine for about 7 years. I'm not really sure what it does. I do get some marbling on my legs and slightly swollen ankles/feet, but nothing awful. It does not seem to help with my tremors.