Parkinson’s disease patients’ short chain fatty acids production capacity after in vitro fecal fiber fermentation 2021

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Inulin beat out resistant starches for butyrate production but both helped.

nature.com/articles/s41531-...

To conclude, this study demonstrates that dietary fiber stimulates butyrate production in PD patients despite decreased butyrate-producing bacteria. However, the butyrate production remains reduced compared to HC. Inulins in contrast to RS increase butyrate production most in both PD and HC, however, the SCFA production start is indicated to be slower in PD compared to HC. Of the vegetables, both the inulin-rich vegetables as the β-glucan-rich oyster mushrooms demonstrated butyrogenic effects. Dietary fiber intake may be a promising approach in PD, but further in vivo research is needed to investigate increased fiber intake’s effect on plasma SCFA levels and motor symptoms.