Why we should be interested in natural MA... - Cure Parkinson's

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Why we should be interested in natural MAO Inhibitors.

SilentEchoes profile image

This is an interesting concept.


16 Replies

I use Zagarese Licorice drops whenever I need help raising [my low] blood pressure - they're also tasty treats and work quickly when kept under my tongue. I also drink organic Matcha (from Japan) daily - a much better version of green tea.

in reply to rescuema

Hi Rescuema - Does Zagarese licorice really help increase blood pressure? My blood is on the low side and I have orthostatic hypotension. Wonder if this can help that. And licorice is a natural moa inhibitor. Could be a double bonus.

rescuema profile image
rescuema in reply to

Yes, it helped me when nothing else would. My BP dropped precariously when I was eating too much cauliflower in my diet - totally anecdotal and no one else ever reports the issue, but I believe it may be oxalate related, so you may want to examine your diet as well. I also noticed ginseng also helps me, but I read some may experience an opposite result - lowers high BP, so its benefit may be adaptogenic.

I use Auragin in case you want to try since there are a lot of fake ginseng products out there. I use ginseng on top of Zagareses when needing extra help. I keep the round drops under the tongue as well, and these taste exactly like ginseng.


in reply to rescuema

Just received the Zagrese licorice and took 3 nibs. How long does it take to raise blood pressure or alleviate orthostatic hypotension resuema?

rescuema profile image
rescuema in reply to

In my case, I noticed it right away, within 30 minutes of being done with the drops. I kept the drops under my tongue the whole time, so I'd say about an hour or so? Did you measure your BP before taking it and measure it again for a comparison?

in reply to rescuema

No I didn’t check BP but I will know when I stand up. Just tried standing up quickly and it seems to work! Hope it’s not a placebo effect. Do you take it multiple times a day?

rescuema profile image
rescuema in reply to

Sorry, I missed your response earlier while distracted. You want to monitor your BP while using licorice so that it doesn't shoot your BP dangerously high - this can happen easily, and you should also watch for potassium level so that it doesn't get too low. Get a BP monitor (I like Omron) if you don't have one. I haven't had a BP issue since correcting my diet but mostly used it before sleep. Good luck!

This article makes the claim:

"Why We Need New MAO Inhibitors...The downside to MAO inhibition is the adverse side effects that often come along with their long term use [7]."

Yet the reference that is given to support this claim says nothing of the kind. There is a legal maxim applies here: Falsus in uno, falsus in omnibus.

That's a pretty broad paint brush you're using.


You are right. I did paint with an overly broad brush. I do agree it is useful to be aware of natural MAO inhibitors for various reasons.

That said, I was offended to my core by an apparent lie about something of utmost importance. If prescription MAO-B inhibitors do have adverse effects that arise with long-term use it is of vital importance to those of us who use them to know what they are and under what conditions they arise. To falsely assert this idea as an excuse to write about natural versions is a bannable offense by this writer, in my opinion.

Relevant articles to review.

"MAOIs prevent the break down of tyramine found in the body as well as certain foods, drinks, and other medications. Patients that take MAOIs and consume tyramine-containing foods or drinks will exhibit high serum tyramine level.[13][14] A high level of tyramine can cause a sudden increase in blood pressure, called the tyramine pressor response.[14] Even though it is rare, a high tyramine level can trigger a cerebral hemorrhage, which can even result in death."


"Side effects of MAO-B inhibitors:

Each medication has its own set of possible side effects. Selegiline (found in Eldepryl, Carbex and Zelapar) may cause dizziness, headache, confusion, nausea, insomnia, dyskinesia (uncontrolled, abnormal movements), and agitation. Rasagiline (found in Azilect) may cause increased dyskinesias (uncontrolled, abnormal movements), orthostatic hypotension (falling blood pressure that occurs upon standing), headaches, joint pain, and indigestion."


True. If a person uses MAOIs they need to be aware of the dietary restrictions.

However, eating healthy fresh food isn't really a restriction. I believe the potential benefit of MAOIs outweighs the risks when appropriate lifestyle and dietary changes are made. This is why I presented the information for people to consider and decide for themselves.


*Edit. The side effects you cite are for pharmaceutical drugs. The article I referenced lists naturally occurring MAOIs from supplements. I think we can all agree that naturally occurring dopamine from mucuna pruriens is not the same as synthetic levodopa/carbidopa, even though they both boost dopamine levels. This is the same principle for naturally occurring MAOIs vs drugs like selegiline.

"The side effects you cite are for pharmaceutical drugs." - yes, the myriad adverse side effects.

I agree and prefer the natural route whenever possible. Besides, I love my daily tasty matcha but even that I need to be careful not to go over 2 cups.


The sunlight article is nonsense.

SilentEchoes profile image
SilentEchoes in reply to MarionP

Do what you please.

MarionP profile image
MarionP in reply to SilentEchoes

If you say so, thanks for the permission.

You know, you're not "Letting It Be."

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