Has anyone noticed??

[laglag]

Has anyone noticed there seems to be more posters on here that are being diagnosed in their 40's?

[RogJen]

I was dxd at 47!

[laglag in reply to RogJen]

I was diagnosed at 46, almost 18 yrs ago, that's probably why I noticed.

[Fed1000]

It is a right intuition, I too have noticed many "new entries" unfortunately. A survey might be useful in this regard.

[laglag in reply to Fed1000]

I would be curious to know but I think on this website it would be difficult because not everyone would reply, more than likely mostly the young ones. It may be something to add to a larger survey though. Maybe there is a reason more YOPD's (Young Onset PD) are being diagnosed earlier. Is it environmental reasons or we're just better at identifying the symptoms?

[Fed1000 in reply to laglag]

Unfortunately there is a considerable drop in the age of the diagnosed and the main suspect of the cause seems to be precisely pollution at all level. I think that the increase of YOPD has given impetus to the search for new treatments because a young worker with PD is a huge cost for the national health system as in most cases he is forced to retire.

[Somic67 in reply to Fed1000]

I was in my 40th year, precisely.

Food type and quality (also polluted) impact on Gut microbiota.We eat too much and too bad.

Pollution is partially out of our control while food quality, quantity and life style are almost 100%

[Fed1000 in reply to Somic67]

Perfect.

[AmyLindy in reply to laglag]

PD is Largely Environmental - The BOOK, Ending Parkinson’s Disease is a Call to Action. EndingPD.org to get the details!

[pdpatient in reply to AmyLindy]

Second that 👍

Time for human kind to step up.

RKM

[qazwsx11]

Most afflicted people I know are in their 40s. Including me

[Oceanwind]

Some smart person here will find us a link with statistical info. Who keeps such global data , the WHO?

[Hikoi in reply to Oceanwind]

No, not WHO. No one does except Sweden I think. No one else has mandatory reporting of PD (does your country?) so what we have are guestimates often based on drug use.

[Hidden]

I am 45. I am new here. I had symptoms for 3+ years but was in denial until my symptoms became glaringly obvious. I am of course sad that there are so many others with YOPD here on HU but I really hope to make the most of this and connect with others in the same boat. I wish there was an additional group just for YOPD. It is really different to be 45 and facing this than retired and with grandkids.

[laglag in reply to Hidden]

There are YOPD support groups. Here is one in Indiana that I used to go to.

apdaparkinson.org/community...

I've made it for 18 yrs and I'm still doing most things I used to, maybe not so fast, but I still do them. One thing you have to do is keep moving and keep fighting! 🥊🥊

[AmyLindy in reply to Hidden]

There are a few on Facebook for sure! Probably here as well- or start one yourself

[Hidden in reply to AmyLindy]

Thank you for the encouragement. For now I am very grateful to learn from those with experience. I noticed you take sublingual B1. May I ask where you get it?

[Rhyothemis]

BCBS reports that early diagnosis has increased but they don't discuss why:

bcbs.com/the-health-of-amer...

If it is not due to changes in how people are diagnosed, then I would guess it to be pollution- related, though I have wondered what effect certain types of media exposure have on the brain over the long term - specifically, the dopamine releasing effects of social media and video game play. Perhaps the exposure of blue light from screens has an impact. Then there's changes to the gut microbiome to consider (has been implicated in the obesity epidemic).

[Hidden in reply to Rhyothemis]

Thought provoking theory about the dopamine and social media and the blue lights. We are all guinea pigs!

[Kwinholt in reply to Hidden]

There’s YOPD support group in Sacramento California. It’s been available for 3 years with a group of wonderful people. 😊 Karen

[rescuema in reply to Hidden]

In addition to other environmental toxins, I believe glyphosate is a huge contributor as well as the modern antibiotics that contribute to gut dysbiosis combined with bad diet full of empty calories. Be sure to only eat organic food.

[Rhyothemis in reply to Hidden]

There are all kinds of possibilities and I hope they are all thoroughly investigated. That 107% increase in early-onset statistic is truly alarming and I hope public health officials are aware (I guess they would have to be?).

About light, I wrote a bit about it in a blog post but I hope to come back to the topic as I saw a video with Andrew Huberman who said even blind people are affected. The study I discuss in the post had cut the optic nerve in the animals (poor things) so I assumed no influence through the eyes, but if blind people are affected then maybe there was (most common cause of blindness is damage to the optic nerve from glaucoma, not sure if that is equivalent to cutting it completely). Also, blind people suffer from circadian rhythm disruption - so I really have to track down the source of Huberman's statement.

rhyobrain.blogspot.com/2021...

[AmyLindy in reply to Rhyothemis]

Yes EMF, environmental agents , pollution ...

[MarionP in reply to Rhyothemis]

Glyphosate. It's in everything and does concentrate into the soil and water table, bound to a sugar as it is. I was a little while ago slowly perceiving the link, these reaction mechanisms and links are complex and many, and so much work and research in wide areas must be done, collected and apperceived it's quite a chore for the non-specialist, like finding Waldo with Carmen Miranda, but beats working crosswords. Unfortunately I deleted nearly 5 years of browsing history during an upgrade so I might not find it. It was a surprise side direction noticed while tracking down the connection to cancer. Have to think about it over a coke (bad for you but it wakes my brain up). It's to do with the phosphorous-cell growth signalling/apoptosis dual switching system this one gene has, with the energy supplied by the phosphorous ion...and some relationship to a hpa neurotransmitter, aspartic acid perhaps, that would put it in the hypothalamus tree...oh heck.

[Mezzomom1]

I was about 47 when my symptoms started. I’m 65 now and am just starting to become stiffer and having more dyskinesia.

[pdpatient in reply to Mezzomom1]

Thanks for sharing. Can you please tell us about your journey?

RKM

[AaronS]

34 here

[MarionP]

Wouldn't be surprised at all.

[hmm777]

I was diagnosed at 49, although I had many of the symptoms long before that.

[buzbyc]

There is s fair bit of support for YOPD's in the UK, just depends where you live. Feel free to message me and I'll try and point you towards something helpful.

[AmyLindy]

Re: comments here on Environment. Read or visit EndingParkinsons.org Dr Okun and Ray Dorsey/others make it very clear that PD is largely “environmental” and growing at an exponential pace. All the specifics are there and the References are excellent. The BOOK is a Call To Action that I feel we should all take to heart (Or give to those that can)! I agree we are seeing more and earlier detection in large part bc of this environmental/lifestyle “epidemic”.

[Parkinsonjisung]

Diagnosed at 29. Do I win?

[Hidden in reply to Parkinsonjisung]

I am absolutely not making light of your diagnosis. But thankfully you will eventually have the benefit of advancing science bc you are so young. Ten years ago it wasn’t even understood that the gut biome plays a major part in PD. This absolutely sucks now but the future is going to be more bright. And I’m no optimist. The number of studies really point towards that.

My Dad has it and so do I.

I think he had it for at least a decade before we knew. He just stopped being able to write and never told us why and he self medicated with wine every night.

There is going to be help for us that the older generations will not have.

[laglag in reply to Parkinsonjisung]

I wish I could say yes! I think cclemonade gave you a good answer.

[laglag in reply to Parkinsonjisung]

Was your diagnosis long ago?

[Parkinsonjisung in reply to laglag]

5 years but had symptoms 6 years.If im being optimistic, the exenatide trial will be successful and and all our parkinsons will be paused or slowed down dramatically. If I'm a being a realist, the exenatide trial will probably work for some and not for others and may or may not be deemed useful. If I'm being a pessimist, the trial will fail and it'll be at least 2030 before something has a shot at being approved given that there's nothing close to be approved for even a phase 3 in the pipeline.

[laglag in reply to Parkinsonjisung]

Hope your optimism comes out on this one. ☺️

[Ksemple1981]

I was 35. ☹️

[Hidden in reply to Ksemple1981]

Thankfully it typically progresses much slower the younger you are and your generation, (I’m 45) will have a different outcome with the progress being made. Sucks now but the future is looking brighter, ultra sound technology, stem cells, understanding the gut microbiome....on time there are going to be multiple angles by which we are going to be helped.

[laglag in reply to Ksemple1981]

Was that long ago? Research as much as you can. Do not give up. Eat better and exercise more. Keep moving and don't give up. 🥊🥊