Schizophrenia may increase Parkinson’s disease risk

[JayPwP]

A recent study concludes that schizophrenia spectrum disorders increase the risk of developing Parkinson’s disease

medicalnewstoday.com/amp/ar...

[park_bear]

movementdisorders.onlinelib...

"In PD patients, the prevalence of earlier schizophrenia spectrum disorder was 0.76% in regional data and 1.50% in nationwide data. In age‐matched controls, the prevalence in the regional and national data was 0.16% and 1.31%, respectively. The odds ratio for PD after schizophrenia spectrum disorder diagnosis was 4.63 (95% CI, 1.76–12.19; P < 0.01) in the regional data and 1.17 (95% CI, 1.04–1.31; P < 0.01) in the national data. "

The regional data was a small sample which only ended up with 23 patients with both conditions. The national data was a much larger sample and ended up with an odds ratio of only 1.17. They had to include "schizophrenia spectrum disorders". Limiting the sample to just straight schizophrenia was not stat sig.