A Phase 1 clinical trial in the U.K. is recruiting patients with mild to moderate Parkinson’s to assess MODAG Neuroscience Solutions‘ investigational oral therapy anle138b, which seeks to slow or halt disease progression.
The trial (NCT04685265) will be conducted at a single site at Nottingham University Hospital, in central England, according to a press release from Cure Parkinson’s. Researchers are looking to enroll 24 adults, ages 50 to 80, who are able to walk unaided.
More information on enrollment is available here, as well as by email. Patients in the U.K. may get additional information via telephone, by calling 03303 031 000.
“Anle138b is taken by mouth, easily enters the brain, and preclinical research indicates that it is very good at reducing levels of aggregated [clumped] alpha synuclein [protein] inside cells. The reduction of alpha-synuclein in the brain has been reported to reverse Parkinson’s-like motor symptoms in animal models,” Cure Parkinson’s says on its website.
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