Diabetic drug could slow the progression ... - Cure Parkinson's

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Diabetic drug could slow the progression of Parkinson’s disease

Kia17 profile image
8 Replies

“Effects of the alpha synuclein aggregates could be greatly reduced by the anti-diabetic drug glibenclamide.”

selectscience.net/industry-...

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Kia17
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8 Replies
Xenos profile image
Xenos

"It is known that patients treated for type two diabetes have less prevalence of Parkinson’s disease."

Really ?

Parkinsonjisung profile image
Parkinsonjisung in reply toXenos

Yep.. theres lots of research on this. Here's one from last month: parkinsonsnewstoday.com/202...

Kia17 profile image
Kia17

Do you have type 2 diabetes?

pdkid profile image
pdkid

hm, i wonder how accessible this drug is... and what it means to slow it down with it. interesting! thanks for sharing!

Patrickk profile image
Patrickk

[cut-and-paste -- I drop this wherever it may be of interest :-) ]

Bydureon, a repurposed Type 2 Diabetes drug is now in third-stage trials in UK for stopping Parkinson’s in its tracks — results expected 2023. Testing — mice, open label, double blind — has been going on for 10 years and it has been positive every time.

scienceofparkinsons.com/201...

According to a very sensitive test, Homeostasis Model Assessment for Insulin Resistance (HOMA-IR), 2/3 of Parkinson’s patients are supposed to be insulin resistant. IR may be treated with Bydureon (Exanatide). Just an angle that might get us one step closer to Bydureon.

scienceofparkinsons.com/201...

cureparkinsons.org.uk/news/...

in reply toPatrickk

I like your exenatide posts. Appreciate the positivity 👍

Kia17 profile image
Kia17 in reply to

Thank you Chris.

gl2238 profile image
gl2238

Only 10 years, sounds like big pharm is involved. I would appreciate a trial now. forget the mice.

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