Just saw this. Not sure if it is helpful but if you are feeling a bit anxious give it a go and let us know😊
It is a tapping motion on chest with palms meant to soothe.
Just saw this. Not sure if it is helpful but if you are feeling a bit anxious give it a go and let us know😊
It is a tapping motion on chest with palms meant to soothe.
It seems like a proper massage would release enough endorphins and dopamine to make an anxious person less anxious.
Art
So are you saying you should get a proper massage instead, or that this may work like a massage?
At least this is free, you can do it yourself, it is quick and you can do it anywhere, so if it helps a little it might be worth trying, although a proper massage might be even more effective of course if you can get one in these days of distancing!
Hi, that was really surprisingly powerful to do this morning and made me cry. Thank you for posting. I use tapping (EFT) which helps me a lot and can have a similar effect. I understand that massage will be good for some but I have Small Fibre Neuropathy/Fibromyalgia and cannot bear to be touched most of the time so not an option. I'll be using it again, without doubt. Just started Wim Hof's deep breathing too - amazing feeling. Cheers.
Fantastic😊
Just wanted to say I love your profile picture and thanks for all the information on your profile. I am so glad that you are both finding things that help you. The Hardy's DEN are interesting. I use ARG Multi-Vi-Min which seem fairly similar although lower dose per capsule. I cannot tolerate corn and these were recommended as corn free, but I re-capsule them as I can't tolerate carrageenan which is often in HMPC capsules. I don't have Parkinson's but do have neurotransmitter issues and have slow COMT enzyme function. If you get chance some time, I'd be interested to know if your husband's DNA test showed any variant to COMT (or MTHFR). No rush. Thanks and best wishes
Hi yes his mthfr c677t rs1801133 is A.A which means the mthfr enzyme may have trouble performing its task leading to high levels of homocysteine. It is a double mutation so 70% loss of function.
His comt seems to have one mutation so is partly blocked.
His other double mutation is GSTP1I105V. Rs1695 GG is important for detoxification
He has the DDC dopamine SNPs rs112718541 A.A. and rs921451 CC which are both double mutations. And rs1611115 CC which is double plus a few other single mutations in this area . It says defects in this are are the cause of aromatic L-amino acid decarboxylation deficiency which is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Critical outcome BAD high dopamine beta hydroxylase activity.
Also rs 6323 TT MAO-A which oxidises serotonin , dopamine epinephrine and norepinephrine. It says avoid curcumin for this one so no turmeric!
Things they suggest to take for all of these are NAC, B2, riboside-5-phosphate, B3, B5, B6, methyl-B12, molybdenum, probiotics, brocolli and cabbage, cardamom, sage, rosemary, l-methylfolate,D3, manganese, vitaminE in tocotrienol form.
Avoid curcumin, cumin, grapefruit, estrogens, androgens, cholesterol, methyl donors. Alcohol, noise. Some of these seem to be contrary to the recommended list so maybe the genes offset each other? Eg methyl donor.
I do wonder if some of the bad genes live happily with other bad genes which offset each other so long as nothing goes out of balance.
Thank you so much for taking the time to send all that - interesting and helpful.
I think your last sentence really sums it up. The better functional practitioners regularly remind us that gene variants are only theoretical and still need to express. Even if they do, some are possibly beneficial, especially in combination. It seems that a single genomic change may cause an illness directly but generally 'SNPs work in coordination to manifest a disease condition'. I have double COMT mutation, but don't think it is any longer predominant. I found one practitioner who said
'Remember that diet and environmental factors epigenetically change COMT expression despite your genotype, so it is important to understand your current symptoms (and if they are related to dopamine/adrenaline/oestrogen)'. I'm sure that can be applied to any SNP or deletion and we shouldn't therefore treat the SNP, but the effect, if there is one.
I don't know much about the DDC SNP's but presumably they are more significant for Parkinson's. No doubt a complicated relationship between those and MAOA and COMT (which affects MTHFR). Neurotransmitters and Methyl donors do seem to be tricky. I was working my way steadily through my 'variant' results, taking not much notice of the normal ones (except for being pleased that I had some) and then someone asked a question on the Fibromyalgia forum last week which had me checking Vit D genes (VDR Taq and Fok) and it turns out that 'normal' VDR can mean higher neurotransmitters and lower need or tolerance of methyl, when considered in conjunction with COMT. Here is the page in case you want a look resqua.com/702188759/what-i.... But I also have a single MTR SNP which may mean I need more methyl, as well as single MTHFR. I do know that before I started the methylcobalamin and especially the methyltetrahydrofolate I was bouncing off the doorframes, felt like the floor was coming up to meet me, was going increasingly numb and had other neuro signs, which have either gone or subsided. Even Quercetin, which I use to manage histamine, is a methyl donor, so I try to use in moderation. I can only assume that my current need is more for methyl than suffering from excess neurotransmitters.
I didn't know about the MAOA and curcumin so will be cautious with that, thank you. Could explain why turmeric didn't suit me when I tried it as a stand alone supplement. I am still taking it, in fairly low dose, as part of the Kirkman's detox support that I am using. This also has an alternative to NAC, calcium d-glucarate to help with the oestrogen and most importantly glutathione (I also have a gluathione absent gene). Glutathione deficiency seems to be pretty important and strongly linked to ill-health, whether autoimmune or not (including Covid). I tested functionally as well as genetically so know that the combination of whatever has expressed genetically is making my Phase 2 detoxification (including methylation) fairly abysmal, hence the supplementation. I use the natural Vit E too, as a blood thinner, and eat lots of broccoli! Look after yourselves x