Does Sinemet cause swelling of the feet?

[kaypeeoh]

I've been on Sinemet a few weeks. My shoes seem tight enough I need to loosen the laces. But then there's not enough available to tie them.

[park_bear]

Not as far as I know. Here is a cool looking symptom checker offered by Mayo Clinic:

mayoclinic.org/symptom-chec...

[kaypeeoh in reply to park_bear]

I checked that. It's either varicose veins or heart attack.

[Kia17]

Any changes in your daily exercises or walking for the past few weeks?

[kaypeeoh in reply to Kia17]

I had surgery on my leg to remove a Haglund's Deformity; A bony growth the size of a half-dollar. I was in a cast for 6 weeks.

[Kia17 in reply to kaypeeoh]

That might be the culprit.

[kaypeeoh in reply to Kia17]

I was wondering whether Sinemet caused edema of the affected limb.

[Kia17 in reply to kaypeeoh]

No as far as I know.

[Redginger]

My husband's feet and legs are badly swollen but he does not take Sinemet. I believe it is associated with whatever is causing his PD symptoms cause he's never had it before and it correlates with worsening of symptoms this last year.

[TL500]

I think it's the PD's rigidity that make the feet (and legs) less range of movement so we stand or move with strain on the ankle joints etc. I feel that's what happened to me.

[lilibelle]

I just asked my neurologist the same question and the answer was "yes".

[kaypeeoh in reply to lilibelle]

....yes that Sinemet causes edema of the legs??

[lilibelle in reply to kaypeeoh]

yes that it can. I have been having swelling and take both sine met and amantadine.

[Bowling55 in reply to lilibelle]

I've read that amantadine causes swelling also

[kaypeeoh]

Thanks, that makes sense. Because of heel pain I don't do anything but vegetate in front of the TV. The surgeon said wait for the pain to stop rather than working through it. I've read damaged tendons can take months to heal.

Doesn't help that I'm staying with my mom, inarguably the world's best cook. Dad died earlier this year. He was cremated and as a veteran we expected a military funeral before internment. But because of corona the military has suspended all veteran funerals. So for me it's a waiting game here in Colorado Springs.

[jello-legs]

Yes I take Sinemet and have swelling of my ankles and legs. It started soon after starting Sinemet.

[Kia17]

Swelling is a common problem for people with Parkinson’s, particularly for those who have movement difficulties. If you don’t exercise very much, fluid can build up in the feet, ankles and lower legs.

parkinsons.org.uk/informati...

[aspergerian]

Consider:

Cheaper, Simpler, and Better: Tips for Treating Seniors With Parkinson Disease. 2011 pmc.

Uncommonly, PD patients sometimes experience massive lower limb edema provoked by agonists.7,8.

ncbi.nlm.nih.gov/pmc/articl...

[aspergerian in reply to aspergerian]

Also:

Mayo Clinic -- swelling of feet or lower legs. Levodopa (Oral Route) Side Effects.

mayoclinic.org/drugs-supple...

[kaypeeoh]

I copied this:

"... variable degrees of dysautonomia, and hence there is potential for orthostatic hypotension... "

This is why my shoes are too tight. Orthostatic hypotension happens typically from standing too long without movement. Veins start to leak fluid which collects in the protentional spaces that exist between cells. That's edema. Technically it's 'pitting edema'. I pushed on my ankle with my index finger and formed a pit which filled back in over 30 seconds.

In the veterinary world it's a common problem in dogs with heart or valve disease. My own dog developed ascites from a mitral valve disfunction. His belly would swell to the point that he couldn't breathe well. Monthly I would stab him in the abdomen with a large gauge needle and draw out up to 200cc of fluid. Then for a month he'd be back to protecting us from the malevolent squirrels in the yard.

The remedy is walking. But I had ankle surgery 7 weeks ago and still have pain in the leg. The doc prescribed Percocet but I can't handle the side effect of constipation. (sigh)

It's also a common problem in distance runners. I wear size 9 street shoes but need size 11.5 running shoes.

So maybe part of the problem is genetics. I donated blood 3-4 times a year for 40 years. They always checked blood pressure. Sometimes mine could be 70 over 35. They wouldn't take blood till I ran around the gym a while and brought my BP up.

Maybe I need to find special socks that old people use.

kpo

[kaypeeoh in reply to kaypeeoh]

Prolly why I have a lot of headaches too.