Uric acid and PD

[faridaro]

Here is the article by Dr. Greger. Many of us have been aware of uric acid levels and PD connection and here is some more information. I checked my uric acid and sure enough it was low - 3.4, will have to figure out how to bring it up - suggestions are welcomed!

nutritionfacts.org/2019/11/...

[park_bear]

High uric acid is associated with terrible consequences - cardiovascular disease and kidney disease. I sent this "Doctor" an extensive list of journal references proving that point a couple of years ago. I am horrified to see he is still at it. There was a study of the effect of raising uric acid on Parkinson's and that study was halted for futility.

[faridaro in reply to park_bear]

Thank you for sharing this Park_bear - certainly uric acid can be a double-edged sword, however at least I should probably avoid foods/supplements lowering it as mine is already very low. Just would be curious to know other PwPs' levels if anybody would be inclined to share.

[park_bear in reply to faridaro]

Very low is very good. Every time I looked I could not find any studies of healthy people with high uric acid, most likely because there are few healthy people with high uric acid. Uric acid is a waste product, a major component of urine and so named for that reason.

[LAJ12345]

He says soy brings it up so switching from milk to soy might help? What we need to know is whether there is a buffering compound that keeps it in the perfect range if we overdo it a bit occasionally.

[faridaro in reply to LAJ12345]

There has been some controversy over soy milk throughout the years and I am not sure what the latest findings are, but it might be ok in small quantities and if non-GMO unless someone is allergic to soy. Supposedly fermented soy products are better especially for people with hypothyroidism and Hashimoto who may be negatively affected by soy isoflavones if I remember correctly, however this opinion may have changed as there have been a lot of conflicting studies regarding soy.

Buffering compound sounds good if anybody would know what can be used for that purpose.

[honeycombe3]

I have had PD for over 15 yrs and gout for over 8 yrs. I can only pass on my own experience which is that gout is agony. I have never read or heard anything positive about high levels.of.uric acid!

[faridaro in reply to honeycombe3]

That confirms what Park_bear said - thanks for sharing!

By the way, cute username - honeycombe - hope your gout is under control and PD is manageable.

[honeycombe3]

Thanks for that.. If you take Alloprinol you longer have gout.PD?? Util.last 2yrs excellent Now going downhill fast.

[faridaro in reply to honeycombe3]

Sorry to hear that Honeycombe - hope you'll be granted recovery and more better days ahead .

[park_bear]

Here is the paper Doctor Greger based his conclusions upon:

researchgate.net/profile/Ch...

There were a very small number of outliers - about 1% of those tested - of extremely low uric acid levels that did show a significant increase in mortality. Safe to say there was something unusual going on in these cases and it does not suffice as a reason to raise one's uric acid level. The comparison between low-normal levels versus middling levels was mixed and not significant.

[faridaro in reply to park_bear]

Thank you PB for taking time to look at the study and elaborate on the results - this makes me feel so much better! And also I realized that although the number of subjects in the study was quite impressive, it was done in Taiwan which may not necessarily extrapolate to populations of other countries.