I’ve been taking B1 on and off for about a year without noticing any obvious benefits. I have to admit though that my professional and a patient’s behavior patterns are quite different. For a scientist it’s a norm to separate variables and establish all kind of controls. As a patient I am starting “new life on Monday “ fiercely throwing all means together: supplements, diet, exercises and so on. Couple of months ago I run out of B1 and decided it was time gracefully end not working relationships. Within next month things went noticeably worse. I hoped it was a fluctuation after our vacation; but there were no improvement. I ordered a new bottle from Solgar.
Improvement started immediately after 1.5 g in the morning. Hard to believe. I am taking 2x1.5 g a day. The improvement leveled, it’s not that dramatic as on a first day. But it’s a good, solid improvement compared with those couple of months without B1.
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Lana666
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Thank you for sharing this. You are so right. We are all doing so many things to try to improve that sometimes it is hard to figure out what works. Thanks.
Thank you for this update! It is very helpful for other members who run into a similar situation.
Often times, people who respond slowly over a period of a month or more do not realize that improvements have taken place and the only time they become aware of any improvements is when they stop taking B-1 or other people who see them less often make a comment like your voice sounds so much clearer and louder now or your tremor seems to be less noticeable.
The good thing about your post is that you seem to clearly be a B-1 responder, which according too Dr. Costantini is highly suggestive that you have significantly slowed or halted disease progression for at least 7 years as that is his clinical experience with his patients in Viterbo, Italy so far!
I have also come around to it, but only 200mg a day. I found I was getting very internally shaky when madapor was wearing off, and needing more and more. Happy to say that a week of b1 seems to have stopped that and I’m able to keep my dose of madapor down to just 3 half tablets a day.
That's right, all you have to do is stop to see that in a relatively short time you have become way worse. To get back to the way that we were before I think it's better to start with a higher dosage of B1. You can always cut down later on.
If you're a scientist, then you'll also remember that stopping something you've been doing for a while is a change too. Feeling little effect does not necessarily mean there is no effect. Also masking an ongoing decline is an effect, one that your method will not rule out.
Just because your n=1 does not mean your case example has been pointless or has no value, as long as you've still gotten a change with multiple ongoing stable variables but one.
Higher doses are pretty much shown to be harmless. But you do need up to several months before necessarily seeing much obvious effect. If you are too timid with the dose you could be years figuring that out.
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