Tavapadon Lessens Motor Symptoms in Patie... - Cure Parkinson's

Cure Parkinson's

27,463 members28,820 posts

Tavapadon Lessens Motor Symptoms in Patients with Early-stage Parkinson’s, Phase 2 Trial Finds

Farooqji profile image
5 Replies

parkinsonsnewstoday.com/201...

Written by
Farooqji profile image
Farooqji
To view profiles and participate in discussions please or .
5 Replies
francis6 profile image
francis6

Encouraging, thanks for posting.

sharoncrayn profile image
sharoncrayn

IQ:

The study was terminated EARLY. So much for that drug.

Sharon

Farooqji profile image
Farooqji in reply tosharoncrayn

Preparations are underway to start phase 3 in 2020

neurologytimes.com/article/...

sharoncrayn profile image
sharoncrayn in reply toFarooqji

Obviously my mistake or the person who wrote what I read. I thought I had read it was terminated early, but obviously not so from the press release.

sharoncrayn profile image
sharoncrayn in reply toFarooqji

IQ:

This is the problem I was referring to with this drug.

So how did they obfuscate these early results to continue on with another clinical trial? A lack of efficacy in one clinical trial apparently doesn't matter.

Difficult not to be cynical about some of these trials.

"Although a previous study of tavapadon (NCT02687542) was terminated early due to lack of efficacy in moderate to advanced Parkinson’s, the “favorable profile of tavapadon in clinical studies to date” support its potential “both as a monotherapy for patients with early-stage disease and as an adjunct to levodopa for patients with late-stage disease,” said Raymond Sanchez, MD, chief medical officer at Cerevel (which was launched by Pfizer and Bain Capital in October 2018)."

Not what you're looking for?

You may also like...

Phase 3 trial of buntanetap for early-stage Parkinson’s nears end

Phase 3 trial of buntanetap for early-stage Parkinson’s nears end – The last patient completed the...
Veravrida profile image

Melatonin Levels in Parkinson’s Patients May Be Linked to Non-motor Symptoms

See sharoncrayn's response to correct post. Melatonin Levels in Parkinson’s Patients May Be...
pvw2 profile image

Phase 2 Mesenchymal Stem Cell Trial in USA

"A newly opened Phase 2 clinical trial is evaluating adult stem cells as a potentially...
jimcaster profile image

A Clinical Research Study for People with Early-Stage Parkinson’s

If you are over 50 and have been diagnosed with Parkinson's disease (PD) within the last three (3)...
Farooqji profile image

Type 2 diabetes is associated with faster progression of motor and non-motor symptoms in Parkinsons

Type 2 diabetes is associated with faster progression of motor and non-motor symptoms in...