Keep hope alive

[Farooqji]

youtu.be/wWIY_bb-KoY(Not working as expected?)

[shaunaxx]

I think it is a shame they do not mention that the symptoms you see he has is dyskinesia which is a sideeffect of the medication. So he is getting to much dopamine.

[WinnieThePoo in reply to shaunaxx]

Are you familiar with Tom Isaacs and his participation in the Bristol GDNF trials? You appear to be implying that Tom's dyskinesia is optional and avoidable, whereas it was the trade-off he had to accept to control his PD symptoms

Amazing guy - inspirational. Very sad when he passed away recently

[shaunaxx in reply to WinnieThePoo]

I am not implying. I just say it is a shame they do not say it is a medicine sideeffect. Not all with parkinson get diskenesia.

I have seen a video with michael fox where he say he every day chose if he want the stifness from parkinson or the diskenesia from the medicine.

[Enidah in reply to shaunaxx]

Michael J Fox was on one of the late-night programs last month and it was interesting to see that he did not have the dyskinesia but had the tremor. I don’t know if that was an off time that he couldn’t overcome or that was a choice on his part since his wife did most of the talking. Yes, many of us are in the position of choosing the lesser of two evils.

[shaunaxx in reply to Enidah]

Yes and as you can see on the reply below only a few is aware of this.

Do you know if some people stop taking medication and live with the stifness and freze?

[PDConscience in reply to shaunaxx]

A "side effect of the medication"??? Unless/until you're equipped with a study or research to support your claim, presenting your preferred interpretation of dyskinesia's 'chicken-or-egg' origins as established "fact" is reckless and helps no one.

*See: 'Good News, Bad News on Levodopa' - Jan. 23, 2019:

"The most potent drug available for Parkinson's disease, levodopa, treats symptoms of the disease but does nothing to either ease or increase its still-mysterious underlying causes, a new clinical trial has concluded."

Source: usnews.com/news/health-news...

[shaunaxx in reply to PDConscience]

Most people are not aware of the sideeffects.

Some even have tremor as sideeffect.

Look at this random page I found.

rxlist.com/sinemet-side-eff...

So look up the sideeffect for your medication.

[PDConscience in reply to shaunaxx]

You seem to be having a tough time distinguishing well-established 'symptoms of the disease' from 'side effects of the drug'. *Your "random page" fails to support your reckless claims - try again.

[shaunaxx in reply to PDConscience]

Ok it was standing at the bortom of the page.

Try this.

Is there a reson for you to being angry?

mayoclinic.org/drugs-supple...

[shaunaxx in reply to PDConscience]

Here are the side effets of levadopa.

Look at the big overlap with common parkinson symptoms.

anxiety

clenching or grinding of teeth

clumsiness or unsteadiness

confusion

difficulty swallowing

dizziness

excessive watering of mouth

false sense of well being

hand tremor, increase

numbness

unusual and uncontrolled movements of the body, including the face, tongue, arms, hands, head, and upper body

unusual tiredness or weakness

[PDConscience in reply to shaunaxx]

Odd... can't find 'dyskinesia' in the list.

[shaunaxx in reply to PDConscience]

There are no chicken egg as the parkinson comes before the sideeffects from medication.

Btw. Look up the production of adrenaline and see what it is produced of.

[PDConscience in reply to shaunaxx]

So... rather than offering a source for your bold levodopa claims, you're now switching channels to 'adrenaline'??? How can I ever become as "aware" as you if you can't stay on topic?

[shaunaxx in reply to PDConscience]

Try look it up. It is the same subject.

Why are you mad?

Do you have an income selling dopamine?

[PDConscience in reply to shaunaxx]

You've revealed the problem: the complete 6-pack may or may not be there, but you're clearly missing that plastic thingy that's s'posed to keep it all together (best of luck with recovery efforts).