Weird but good mornings

[Airglo1231]

PD Symptoms are almost non existent in the morning????? Then as day progresses it gets worse....anyone have this experience?

[Hidden]

Yes. This is my experience as well. I don't know why it is the case...

[Astra7]

Me too . I think dopamine builds up overnight.

[faridaro]

In my case it's just the opposite - functioning much better in the evening.

[bassofspades in reply to faridaro]

Same here

[Beanie57 in reply to bassofspades]

Again my friend WP experiences the opposite... better in the evening rather than the morning.

[freefallmode]

I experience the same for a short time in the morning, and if I get up in the middle of the night to pee I have no trouble walking or with other movements. Like someone said, maybe dopamine or another chemical build up while sleeping

[aspergerian]

Perhaps some clues:

ncbi.nlm.nih.gov/pmc/articl...

[aspergerian in reply to aspergerian]

More clues here:

ncbi.nlm.nih.gov/pubmed/253...

Write to corresponding author of each study.

[aspergerian in reply to aspergerian]

Another :

ncbi.nlm.nih.gov/pubmed/237...

[aspergerian in reply to aspergerian]

Patients with mood disorders often display abnormal rhythmicity of body temperature, cortisol and melatonin levels, blood pressure, and sleep/wake cycles suggesting circadian rhythm disruption (Wirz-Justice, 2006). Sundown syndrome, also referred to as “nocturnal delirium,” is characterized by worsening of behaviors such as agitation, aggression, restlessness, and delirium, particularly during the late afternoon/early evening, implying a strong association between circadian rhythm and mood regulation (Bedrosian and Nelson, 2013).

ncbi.nlm.nih.gov/pubmed/226...

And:

ncbi.nlm.nih.gov/pubmed?lin...

[Hidden]

Yes. Me too

[Spraguej42]

Me too..

[Maltipom]

Since the beginning, I've always felt better in the evenings. Just another example of just how much this condition can vary among pwp.