Extra virgin olive oil taken with coq10 effects on plasma and protein oxidative status.

[LAJ12345]

researchgate.net/publicatio...

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Olive oil consumption is associated with protective cardiovascular properties, including some beneficial modifications in lipoprotein profile and composition. Coenzyme Q(10) (CoQ(10)) exerts a protective effect on plasma lipoproteins. Aim of the study was to investigate whether extra virgin (EV) olive oil enriched with CoQ(10) affects CoQ(10) levels and oxidative status in plasma and in isolated lipoproteins. Twelve subjects were administered 20 mL olive oil per day for 2 weeks, followed by 2 weeks of olive oil enriched with 20 mg and 2 more weeks with 40 mg of CoQ(10). Plasma and isolated lipoproteins were collected in each phase of the study and subsequently analyzed to assess lipid profile, CoQ10 levels, ORAC assay, resistance of lipoproteins to peroxidation and paroxonase 1 activity. Plasma CoQ(10) levels significantly increased with the 20 mg (+73%) and 40 mg dose (+170%), while the percentage of oxidized CoQ(10) decreased. A significant inverse correlation was found in plasma between percentage of oxidized CoQ(10) and total antioxidant capacity. A lower susceptibility of LDL to peroxidation was also found. Finally, a positive correlation was observed between concentration of CoQ(10) in HDL and paraoxonase-1 activity. EV olive oil enriched with both doses of CoQ(10) significantly affects its bioavailability and plasma redox status. These changes are associated with a decreased susceptibility of plasma lipoproteins to peroxidation associated with a chain-breaking antioxidant activity of the formulation.”

[Moorhen2002]

Sorry it's all Greek to me! I'm still getting to grips with all the abbreviations pwp use in their posts, it would be useful to have a list up of them all for newbies like me.

[LAJ12345 in reply to Moorhen2002]

I think it just means if you take extra virgin olive oil with your coq10 it will protect it so it works better.

Coq10 is a supplement some people take which is supposed to help😊

[Moorhen2002 in reply to LAJ12345]

Thanks LAJ12345 I will Google Coq10 to see what it consists of. 🙃

[PDGal4]

I take 400 mg of CoQ10 daily. I went up to 600 mg, but it gave me a bellyache. So the 40 mg in the study sounds low to me (they come in 100 mg and 200 mg dosages). If I've done the conversion correctly, 20 ML olive oil = about 1/8 cup or 2 tablespoons. I easily consume that a day in my cooking, so good to know it is enhancing the CoQ10, which I do feel reduces symptoms.

[LAJ12345 in reply to PDGal4]

You’re right, it doesn’t sound like much.