I've found three case reports where a person with PD took antibiotics for an unrelated reason, and found their PD symptoms to be essentially, and inadvertently eliminated...anyone out there have a similar experience? I'm almost ready to try it out, without the unrelated condition...most likely doxycycline ..?
Antibiotics and PD symptomology - Cure Parkinson's
Antibiotics and PD symptomology
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Ronshere
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I've come across this story before - I'd love to try them but need a prescription (in the UK)
I saw antibiotics for fish on amazon but I'm not quite that stupid! 🐟🐠
I do not doubt these reports but it does not work for everyone. I have had to take antibiotics on certain occasions and it did not do anything for my Parkinson's.
Do you have those cases handy?
Definitely not eliminated but somewhat reduced. I took doxycycline for leg infection for 10 days .
Ronshere
Interesting point, is there a possibility to learn more about these cases? Study was done on mice that confirmed this: sciencedaily.com/releases/2...
Here is my antibiotic/PD summary with links to human case studies appended to end of report (direct links don't seem to function from within my report)...
Antibiotics and Parkinson's
Proposal…
To undertake a low dosage regime of doxycycline as a case study (N=1) to determine the effect on PD.
Background…
Three case studies here, here and here have been reported in the medical literature related to the impact of oral antibiotics on PD. In each a substantial reduction/elimination of symptoms was reported to have been short term impactful, and long term effective. In all the patient had been treated for a different condition and the consequent impact on Parkinson's symptoms was unexpected. Each had been diagnosed with PD several years previously.
A 2017 Brazil paper showed antibiotic alleviation of PD symptoms in a mouse trial. A second report suggests doxycycline may offer hope for treatment of PD.
A 2016 report links H-pylori to both PD and to medicinal uptake. One could intuit that antibiotics down manage H-pylori, leading to improved levadopa uptake and PD symptom alleviation.
A 2016 Caltech report connected the gut to PD in mouse studies. This would tend to support the relationship between oral antibiotic treatment and PD.
Ron MacKenzie
December 24, 2018
Case Studies
journals.lww.com/clinicalne...
Please link the case reports. I am pretty certain research is far enough down the road to know PD is not a simple bacterial infection. Antibiotics misuse including overuse is a major public health risk.
That said, I attribute my PD onset to antibiotics, as I have posted elsewhere, and possibly my microbiome regeneration success to them too.
A typical broad spectrum antibiotic will devastate the gut microbiome. Largely clean it out for a fresh start. It won't clear out everything, like some stubborn C diff infections, but does leave a potential clean sheet on which to write with good bacteria. If antibiotics are followed by good probiotic rich diet it may help shift the microbiome and that may account for the reported cases
Please provide links to them
Ps. Interesting article in today's guardian related to this subject
theguardian.com/science/201...
Here is my antibiotic/PD summary with links to human case studies appended to end of report (direct links don't seem to function from within my report)...
Antibiotics and Parkinson's
Proposal…
To undertake a low dosage regime of doxycycline as a case study (N=1) to determine the effect on PD.
Background…
Three case studies here, here and here have been reported in the medical literature related to the impact of oral antibiotics on PD. In each a substantial reduction/elimination of symptoms was reported to have been short term impactful, and long term effective. In all the patient had been treated for a different condition and the consequent impact on Parkinson's symptoms was unexpected. Each had been diagnosed with PD several years previously.
A 2017 Brazil paper showed antibiotic alleviation of PD symptoms in a mouse trial. A second report suggests doxycycline may offer hope for treatment of PD.
A 2016 report links H-pylori to both PD and to medicinal uptake. One could intuit that antibiotics down manage H-pylori, leading to improved levadopa uptake and PD symptom alleviation.
A 2016 Caltech report connected the gut to PD in mouse studies. This would tend to support the relationship between oral antibiotic treatment and PD.
Ron MacKenzie
December 24, 2018
Case Studies
journals.lww.com/clinicalne...
omicsonline.org/open-access...
newscientist.com/article/mg...
I guess antibiotics change the gut microbiome where the PD symptoms are consequences of that change so a person may feel better.
A similar thing happens with SIBO, but it's temporary & certainly not recommended. You don't want to kill off all of your gut bacteria; you want to heal it by getting the right bacteria in it. Still, an interesting clue.
Some folks with Lyme are misdiagnosed as having PD instead. The antibiotics could curb the Lyme for a time and therefore symptoms could temporarily improve.
Well, before I accepted my PD diagnosis, I was hoping that my symptoms were due to Lyme disease. Pursuing this hope, I took massive quantities of various types of antibiotics. I mean, years of antibiotics. This included four consecutive months (120 days in a row) of IV doxycycline.
None of this did anything for my PD symptoms. I think (and I am NOT a doctor!) that antibiotics would only work if you had some kind of meningitis or other bacterial infection that was causing brain inflammation, which can cause various neurological problems.
What city and state do you live in?
You could ask your doctor run tests for Lyme disease (you'll want t make sure to your doctor uses IgneneX Labs Palo Alto, CA for this since most labs don't know how to properly test for Lyme. Also, there are other possible bacterial and viral causes of brain inflammation. IgneneX Labs can also, if you call them, give you a list of "Lyme -literate" doctors. And doctors who actually, truly know how to treat Lyme are rare, and their experience with Lyme makes them competent to also check for other possible causes of brain inflammation. Such doctors would also be able to refer you to a (hopefully) open-minded neurologist.
Brian Rosner has published some good books on Lyme, and Dr. Brian Fallon at Columbia U has done some excellent Lyme research. Again, I'm no suggesting you have Lyme; just that it is one well-known cause of brain inflammation. Also, it is a very complex disease, so if you learn about it in depth, you will learn about how to investigate other possible causes as well.
I want to encourage you to really open your mind and investigate any and all possible causes of your symptoms. Brain problems are complex, and those of us who have them, have the responsibility - we can't just leave it to the doctors - to know how our brains work - so that we can be empowered to know the full range of possible "why's" that our brain is not working - so that, hopefully, as a team with our doctors, we can get better.
Good luck!
Ben
recent study on the subject
A Case of Lyme-Associated Parkinsonism: Could Timely Treatment Have Saved a Man’s Life?
The Diagnostic Disaster
The heart of the Parkinson's diagnosis is ruling out other neurological disorders, since these symptoms are found in many disorders. Most importantly, the symptoms above can occur in neurological Lyme.
As has been very well described, neuroLyme can present in a hundred ways and is called the "Great Imitator." Yet many Neurologists do not take this seriously and never consider Lyme in Seizures, ALS, Migraines, MS, Strokes or hundreds of other neurology or psychiatric diagnoses.
Since Lyme is the leading vector illness in the US, and lab tests are commonly utter junk (See 20 articles on this fact on my web site), it is easy to miss. Lyme with Parkinson's symptoms looks exactly like real Parkinson's. Exactly!
Parkinson's is progressive over years. But so is Lyme.
Parkinson's waxes and wanes, and so do the spirochetes of Lyme.
Source: personalconsult.com/article...
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