thiamin hcl LUNCH dose

Breakfast first dose, it takes four hours for levels to drop. Taking second dose at lunch keeps thiamin hcl level in blood high.

ncbi.nlm.nih.gov/pmc/articl...

[park_bear]

It takes four hours for the blood plasma level to peak, but even after 10 hours there is still a substantial concentration. I would rather take my second dose in the evening to get as much coverage over 24 hours as possible. Understood that high-dose thiamine can interfere with sleep and some people must take their second dose earlier for this reason. I did have to cut my evening dose back to .8 g.

[Isthistheone in reply to park_bear]

Any need to know and therefore test thiamin blood plasma levels?

[park_bear in reply to Isthistheone]

I have never tested mine. I have the impression Doctor Costantini goes solely by the symptomatic response, but I am not certain.

[Hidden in reply to Isthistheone]

Dr. Costantini has found that many of his patients show normal range thiamine levels before starting B-1. Once started, the levels are very high , reflecting the high dosing.

Art