image for The locus coeruleus story in PD: norepinephrinergic system, Zarow, hypertension, hypotension

[aspergerian]

Trying again, from Zarow et al 2003.

[hopeful88]

The last sentence is pretty telling. "These findings suggest that greater attention should be given to lessening the depletion of acetylcholine producing neurons in PD"

This is correct. Acetylcholine is the body's most important neurotransmitter. PD and related disorders have significant stress and die-off of the cholinergic neurons over time. This plays a big part in cognitive and speech dysfunction, and whether or not your PD will convert to MCI and dementia

A combination of creatine and co-q 10 offers robust protection to the brain, preventing the development of cognitive issues and dementia

ncbi.nlm.nih.gov/pubmed/257...

[SilentEchoes]

Glutathione is the brains most prevalent antioxidant. It's a good place to start.