Urgent: I'm on pramipexolé er4.5 mg plus... - Cure Parkinson's

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Nimvas5962 profile image
15 Replies

I'm on pramipexolé er4.5 mg plus syndopa cr125 TDS changed over recently. I'm suffering from severe pain of the affected side and twitchings and numbness. Cud it be due to pramipex er side effect

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Nimvas5962
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15 Replies
BUZZ1397 profile image
BUZZ1397

I guess it might be that side-effect of Syndopa, the literature says it can cause leg pains. But what does TDS mean? I am not familiar with that acronym. Contact the doctor as soon as you are able about the pain and twitching it might be the Syndopa.

Nimvas5962 profile image
Nimvas5962 in reply toBUZZ1397

Not the pramipex

.....??????

Hikoi profile image
Hikoi

Its hard to respond because I dont really follow, you changed over from what to what? Are these both new meds? How long have you been on them etc.

park_bear profile image
park_bear in reply toHikoi

Right, and need to know how many syndopa cr125 daily.

BUZZ1397 profile image
BUZZ1397

What are the side-effects of Syndopa Plus Tablet?

The most commonly reported side-effects of Syndopa Plus Tablet are unsteadiness, back or leg pain, hot flashes, increased blinking, spasm of eyelids, and grinding of teeth

Nimvas5962 profile image
Nimvas5962 in reply toBUZZ1397

Onlyparaesthesia of LTE leg old complaint never resolved.Sent to another mov disorder specialist who said it is heralding sign of off time so whenever it comes I had take syncopa. This I dif which resulted on dyskinesias .so pamipex 1.5,x3 became 4.5 errr.the dyskinesoas stopped.Next step would have been to introduce credit form which I did as my doctor. Flatly told me to go somewhere else0

Bailey_Texas profile image
Bailey_Texas in reply toNimvas5962

Are you taking syncpoa only when you have symptoms or at regular times throughout the day. please try to list your symptoms.

Nimvas5962 profile image
Nimvas5962 in reply toBailey_Texas

Right now on advice of Neuro only when symptoms appear which is every 3hrs

fwes profile image
fwes

Pramipexolé is the generic name for Mirapex. Search these pages for Mirapex and find numerous writings on adverse reactions to Mirapex and difficulties with withdrawal. My reactions were confirmed since the symptoms went away after withdrawing from Mirapex.

My adverse Mirapex symptoms: fatigue, muscle pain, daytime drowsiness including falling asleep without warning (even while driving), audio hallucinations, double vision, 130% swollen lags, which led to 2 major cellulitis infections, and a 95% clogged major artery. The symptoms came on gradually over a couple of years, so we did not immediately attribute them to Mirapex, and instead blamed Parkinson's. Since withdrawal, I no longer have any of these symptoms.

For me Withdrawal was a 2-year ordeal, with severe fatigue for the first year. Search these pages for DAWS (Dopamine Agonist Withdrawal Syndrome). My Cardiologist exclaimed "You mean , they still allow this stuff on the market?!"

Nimvas5962 profile image
Nimvas5962 in reply tofwes

Please see.my reply.my symptoms same as yours except no swollen legs.I tried reducing from 4.5 to 3.5 for 2 days. Major upheaval,tremors major emotional lability tearing at minor things so I chickened out. Waiting for the new doc to be more supportive

isis6361 profile image
isis6361

You may just need to reduce the dose. The pain maybe dystonia due to overload.

Nimvas5962 profile image
Nimvas5962

Thank you I've done just that.My savior again is silvestov who suggested I take high doses sublingual. Vit b12 hardly had I taken 3000mcg there is total let up of pain except for a numb ball of great toe Also to control dyskinesias I'm taking smaller doses of syncopated plus 100/25 .today except for morning telekinesis for 1hr I 've settled.Another thing S suggested was. to up the doses of DHA and also do some mag supplements.

What would I do without S. I'm praying this increase in on time lasts. Another trick I learnt is to try a supplement called citacholine or also called cod choline Narrows formula 250mg twice a day.It increase the dopamine receptor density in approx 30 days and thus leads to decrease in total dopamine dose.....Laurie Mischley

She is a fantastic person wonderful friend who has stood by me in my moments of crisis. So temporarily I've managed to bang the COBRA 'S Hood down.I also. am extremely grateful to all of you who responded to my desperate call for help

God bless u all

Nimvas5962 profile image
Nimvas5962

As regards Morales I'm well aware of what you say as also daws Laurie warned me but as you know it cannot be done without medical supervision,and there is quite a chance I may not be able to get off it.

I want all of you to know that if you have a good Neuro stick by him and don't let him go.It has been trying times for me the agony the pain the sleeplessness which I'm sure only u people my true friends will understand.How you get hit when ur Neuro tells you I've tried I failed get lost.Another tells me in front of my wife that u have wAsted 7 years of your life and have not reconciled to the disease.

Since then I've found somebody who I think just maybe will help me.May I tell you just off records am.a medical professional.

I've decided to put pen to paper so that I can chronicle what I'm going thru which all of us go thru..

.

Pd he is a lost case,, you must understand that u have a Neuro degenerative disease the only way is down. Damn it we know that you don't have to bore that into our heads and bring our psyche down

amerrescue profile image
amerrescue

Check with your DR about interaction or allergic response. Regarding pain: Sometimes I would pass out unconscious from pain. I was in severe pain for up to 9 months, at a single time, without 5 minutes of peace. I was prescribed narcotics but refused to take for fear of becoming an addict. I was prescribed marijuana. It took my Primary Care Dr 6 months to convince me to take Marijuana /CBD. I am glad I did. It never got me 'HIGH'. It only makes people who are not in extreme pain 'High'. If you are in pain:

IT just lifts you up 'from the depths' to make your pain; either 'go away' or become 'bearable'. Basically, Marijuana has 2 component categories: THC and CBD. THC 'picks up your 'mind' and CBD 'picks up your body', by reducing inflammation (pressure on the nerves) and many other beneficial results.

Nimvas5962 profile image
Nimvas5962 in reply toamerrescue

What is your diagnosis ,age of onset, years into the disease that pain started, any supplements,.mrijuana no go. I can't go to work excuse me carrying it or smelling of it.

Thank you for your response

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