NAC seems to be a game-changer in PD

[SuperMNew]

This is an interesting study. Well worth reading: ncbi.nlm.nih.gov/pubmed/273...

[Astra7]

I have been trying it for around 8 weeks now and it does seem to be helping especially with brain clarity. My stumbling speech has improved. I am quite optimistic as my symptons are virtually gone except when stressed, and my arm still doesn't swing! I am in the early stages of Parkinson's though so it might not last.

[SuperMNew in reply to Astra7]

This is great news, Astra7. I know that it takes time to heal, so hopefully the research will soon reveal just how much NAC is needed to improve your PD. Blessings!

[999---666 in reply to Astra7]

n-acetylcystine (nac) is a precursor to glutathione, have you tried it? i'm looking at it, first glance, it's not without hazards/discomfort.

[park_bear]

Oh yes, this study has been cited before on this site. Doesn't hurt to cite it again. I get the NAC in powder form and add 24% by weight calcium hydroxide (also known as pickling lime) to get pH neutral. Pure NAC is quite acid and I found it irritates my sensitive urinary tract. I then cap the mixture up in 00 caps for a bit more than 600mg per dose.

[SuperMNew in reply to park_bear]

Has the NAC powder helped you?

[park_bear in reply to SuperMNew]

It has helped ... with a prostate condition!

I can't say it has actually helped with the PD. I found the study convincing so I am keeping the faith. I chose to cut back from 3x / day to 2x / day because it was thinning out my already scarce saliva which may have contributed to dental problems.

[Motal]

Hi Apologies in advance if this has been covered before. How much NAC do you take per dose and how many doses daily? Also, if I don't want to go the pickling lime route, any recommendations on a ready made form that is less acidic ?

[park_bear in reply to Motal]

My dosage was a bit more than 600mg each time as I said, 2-3x/day. That is also the typical dosage in prepared capsules. From the cited study: " Subjects took the 600mg NAC tablets 2x per day on the days that they did not

receive the IV NAC."

[Astra7]

I am now taking 2 x 600mg per day as 1 didn't seem to be doing much. I just take the capsules.

Have just noticed that they stink! Could not smell them before!

[Motal in reply to Astra7]

Astra7. Thanx. Perhaps being able to smell them is a sign they work??

[Astra7 in reply to Motal]

I'm hoping!

[p-oui in reply to Astra7]

Yes maybe this is great news! Astra, any difficulty taking the NAC? I had nausea and sleepiness (600 mg 2 x day per the trial)

[Astra7 in reply to p-oui]

My mouth is a little dry and I am a bit more constipated than normal, but all relatively minor.

[Astra7 in reply to p-oui]

Did you have any improvement or did you have to stop too quickly?

[p-oui in reply to Astra7]

I didn't notice any improvement and the nausea probably created a little stress but I was only on it for a few days. I dropped the dosage to 600 but was still nauseous. I would try it again if I thought it would help with my tremor.

[Astra7 in reply to p-oui]

I take mine at night so perhaps the nausea passes as I sleep. Also someone mentioned the acidity which might be your problem and can be balanced with various things.

I think it helps me sleep too.

[p-oui in reply to Astra7]

Now why didn't I think of that? BTW if you have tremors has it helped?

[p-oui]

You might also want to check out this post:

n-acetyl cysteine (NAC) parkinsons clinical trial accepting now