Sinemeth and blodpressure

[snorre]

Hello

I'm wondering if anyone have notist a connection between taking sinemeth and blodpressure.

Same question on eldepryl

[Prayingforacure]

My husbands BP use to be all over the place on readings, I never could find out why. I took him off all his meds in December 2012 and his bp readings have been in the normal range. Have you talked to your physician about whatever is happening.

[snorre in reply to Prayingforacure]

I have bougth 2 different kinds of messuring the blodpressure and are about to buy a third one.

As you say i get different readings all the time.

Thanks for dealing your experions with me.

[Hikoi]

Yes BP often goes down with medication but also parkinsons can cause this. The autonomic nervous system (control system for heart, bladder, gut, etc) is affected by Parkinsons but i dont understand how.

My BP is very changable throughout the day. I think it depends on my medication. It doesnt cause me problems but some people get faint or light headed especially going from lying to standing.

[snorre in reply to Hikoi]

Well , my problem is that if i'm going fast from lying to standing i'm almost loosing controll ,and readings on blodpressure shows "error" , hehe

At the same time in avrage my blodpressure migth be more than 140 (pumppressure).

The problem is that blodpressure medisin of today lowers both the pressure and thats a big risk , not only to have to high pressure but also to low pressure.

circ.ahajournals.org/conten...

" ISH is the most common form of hypertension in those older than 65 years. Because this segment of the population is expanding so rapidly, ISH will soon be the most prevalent form of hypertension. "

"However, lower diastolic pressure is also dangerous. In the analysis of the course of >7500 elderly patients with ISH who were left on placebo during multiple randomized controlled trials (RCTs), a continually higher death rate was seen, as expected, with progressively higher systolic pressures on entry but, surprisingly, similar increases in mortality were seen with progressively lower diastolic pressures on entry. When diastolic pressures are lowered too much by antihypertensive therapy, similar increases in events have also been seen. Therefore, the high systolic pressure must be lowered, but caution is needed not to lower the already low diastolic pressure much further."

" Therefore, caution is advised in treating those with ISH, who obviously start with already low diastolic blood pressures"

"In conclusion, the need for effective antihypertensive therapy for the many millions of elderly patients with ISH has been reconfirmed by Fagard et al.1 However, their data warn of the need to first establish the presence of out-of-the-office hypertension. Once established, ISH should be treated gently by bringing the systolic blood pressure to near 140 mm Hg while ensuring that the diastolic pressure is not lowered much below 70 mm Hg. Those with even lesser elevations of systolic pressure may require active therapy if they are at high risk because of concomitant diabetes, renal dysfunction, heart failure, etc.In the future, drugs other than those currently recommended may have a more selective effect, lowering the elevated systolic levels but not reducing the already low diastolic levels"

There is a new medisin in clinicaltrial 2a named SER100 that will be public within 2 mounts that is design to only reduse the pumppressure and i hope this will turn positiv out.

norwegian company named serodus

[BillDavid]

After diagnosis with PD, also diagnosed with high blood pressure, been on meds for high BP since then.

Take Sinemet and selegiline (eldepryl) now as well as High BP med..

BillDavid

[JohnPepper]

Hi snorre. Eldepryl, aizilect and parkilyne can all cause high blood pressure. What you have to be careful of, is eating warmed-up food, over-ripe fruit and mature cheese. You can Google - Tyramine, food and see what other foods contain tyramine, which is the chemical in the body that causes this. You will have to check your BP regularly, but don't stop taking the medication, as that is doing you a lot of good.

John

[Susie01]

I take both Azilect and Sinemet, both will affect blood pressure and does PD. I have to watch for highs due to the Azilect and lows with the combination of the two meds. My systolic is typically a little high, the diastolic with bottom out most of the time, more dizziness and unsteadiness...