Naltrexone low dose

[Golda]

Hi - I've just signed on, so please excuse me if it's already been discussed!

Have you heard of Naltrexone Low Dose? It is supposed to be a miracle drug for Parkinson's. MS, Cancer, Arthritis - the list just goes on.

ldnresearchtrust.org

Please have a look!

[movinngroovin]

Read- Honest Medicine. I am on it now for 6 months -it is supposed to suspend the progression. I will stay on it until the "cure" comes.

[Pete-1]

If there was such a magic potion as you describe that can cure many ailments not only PD but MS and my word cancer too then there would be Nobel prizes, every news channel on TV in the world wouldn't shut-up about it . There'd be dancing and singing in the streets. You name it, it would be happening.

No I'm afraid its back to the god old proper rigorous scientific endeavours with double blind trials by the skipful, years of experiment into precise circumstances its use is appropriate, which is the correct dose, what incompatibilities exist between LDN and other drugs, what side effects arise and so on.

Almost without exception if something sounds like it is too good to be true then it is exactly that.

Perhaps LDN will be found to be of use but not in treatment of many diseases. Cancer is likely to be defeated eventually in most cases by a whole myriad of different drugs for the different types of cancer and other factors.

[Moodyblue in reply to Pete-1]

No-one is suggesting that LDN is a cure for anything, but only that it appears to slow or even halt progression of many diseases. The rigorous testing required is expensive, and, since Naltrexone is out of patent and cheap, no drug company will finance that testing on something with no profit potential.

Maybe it will turn out to be 'too good to be true' but in the meantime I'm hoping to be able to try it. My GP has never heard of LDN and is researching it. I go back to him on Thursday to find out his opinion.

I firmly believe that if research into medications and cures for diseases such as PD was NOT profit seeking an affordable cure would be here by now. But who in his right mind is going to shoot the goose that lays the golden egg?

[FMundo in reply to Moodyblue]

Did your MD prescribe NDL? What were the arguments or rational supporting that decision?

[Moodyblue in reply to FMundo]

No, none of my medical practitioners will consider prescribing LDN because it is not "approved for treating PD". This despite my saying that I will accept full responsibility for any detrimental consequences and also stressing that I didn't care if it killed me. I just cannot understand the attitude of these people - they are terrified of taking even the slightest gamble.

[FMundo in reply to Moodyblue]

There is absolutely no reason why you can't get a prescription for LDN. There are naturopathic doctors all over the place who will prescribe it. You will have to obviously go in for a consultation and perhaps you'll have to do that on an annual basis. To my mind there is NO JUSTIFICATION for your PCP or Neurologist to refuse your request unless they can provide you with COMPELLING evidence that the drug would be harmful or interfere with other therapies. Indeed, the problem you really have is "how you feel" about your physician, when they deny you a prescription based on "no peer reviewed material on the drug." When they haven't reviewed the supporting material you've provided... when they are not supportive in providing emotional support to you, a person who has a fatal, degenerative disease, for which there is no cure. PD is not a walk in the park.

After careful research and thought on my part, I am convinced that LDN will either have no effect, or a positive effect in slowing PD FOR ME. And guess what, I GET TO DO WITH MY BODY WHAT I WANT TO! MD's that refuse to support my effort to fight the disease get their walking papers. Naltrexone is FDA approved. Off Label prescriptions are done by MD's all the time.

By the way, I have always been very reluctant to take drugs... even aspirin... unless I have a real need. LDN has eliminated my serious back pain, boosted my spirits, seems to have slowed my symptom progression.

On a personal note, all of what I've talked about above in terms of MD's and prescriptions I've lived through. So my advice is "get going and stop pussyfooting around."

[redread in reply to FMundo]

FMundo, I'd be interested to know what dosage and in what form are you planning to take LDN? Pills, powder? Under 5mg? I would like my husband to at least be able to try LDN. LevaDopa has terrible side effects on him and the other med he tried for one day made him ill. I'm also looking for a naturopthic (ND) practitioner in the Washington, DC area

[michaela13 in reply to Pete-1]

The drug companies aren't going to profit from it. Money talks. Do the research. I'm going to try to get it.

[munnings]

Hi Golda,

After two years of contemplating taking LDN I decided recently to give it a go. I have now been on it for three weeks (steadily increasing the dose from 1mg week one to eventually 4.5 mg). I don't know if it is a coincidence but the bladder problems I've experienced for the last 4 years (incontinence on a regular basis and gradually getting worse) are markedly improved. I can find no other explanation for the change. At such a low dose and the reasonable cost of this medication, I am certainly going to carry on taking it until otherwise convinced not to.

[gurdeep11]

can u find it Otc or need slip, how much it costs and u guys take low dose as it comes in 50 mg

[silvestrov in reply to gurdeep11]

Naltexone is not effective at large doses for Parkinson's disease, say 50 mg. Low Dose Naltrexone is taken at doses from 1mg to 4.5 mg right before bed is effective for Parkinson's disease. The problem is to find a doctor who will give you a prescription and the key is to tell the doctor you will be taking the medication at your own risk to relieve responsibility from the doctor if anything goes wrong. LDN can be purchased online for about 50 dollars a month but it can be less with a prescription - as low as 20 dollars a month. LDN will need to be taken indefinitely since this is not a cure for PD, but a therapy to decrease symptoms/halt the progress of the disease.

[silvestrov in reply to silvestrov]

Also, LDN has to be specially compounded, purchased a specific compounding pharmacy and it is best to purchase it from a pharmacy with past experience of making LDN.

Here is an audio link that will give you all the answers to your questions:

blogtalkradio.com/parkinson...

[munnings]

I live in the uk and I had a phone consultation (costing £30) the doctor then issued a prescription to the chemist. The LDN was then posted to me from the chemist which is based in Glasgow, it comes in liquid form. The cost of a months supply is £18. Am not sure how it works in other countries. Have heard some GPs and Neurologists will prescribe but I haven't gone down that route.

[FMundo]

Sounds like YOU are not a LDN enthusiast.

[Moodyblue in reply to FMundo]

Whatever gave you that idea?

[Moodyblue]

Once would have been enough! And just because it appeared to not work for you does not mean it doesn't work. We are all different and react to treatments in different ways. We are warned that it could take a year for benefits from LDN to be felt; also that the most important result is a slowing of the progression of the disease - very difficult to monitor, so you really are not qualified to make the claim that it doesn't work. As for the 'new drugs' - if you're happy to take more poisons with vicious long term side effects then go ahead, but I for one would prefer to try the low risk approach.

[Moodyblue]

Shame it cost you so much more than it is costing me here in UK. It costs me only a little more for a whole year. My doc's attitude was similar to yours, despite loads of anecdotal evidence which suggests that LDN works for many.

8 weeks is nowhere near long enough to establish whether it will work or not - a year is nearer the mark.

I'm glad to see your current meds regime works well for you with no side effects, and hope you'll still be saying that after 20 years on them.

As you say, many more drugs are on the way, all costing a fortune and with unknown consequences. Just suppose that eventually LDN is proven to work - even if all it does is slow down or halt the progression of PD - I for one would be angered that I hadn't tried it. I'm not expecting miracles - I don't expect to feel better even, but I do hope to slow down the sliding down the slippery slope I'm on at the moment. Time will tell ... I wish you luck.

[Moodyblue]

How many people do you know who have actually tried it for long enough? I don't personally know any but am taking notice of any anecdotal evidence I can find, both positive and negative. I am well aware that we are all different - I'm 62 and have been living with PD for 20 years so I've learned a bit about it in that time as well as experiencing the consequences of taking some of the existing PD meds. What worked well for me ten years ago won't touch it now which is why I seek an alternative. What makes it worse is that as well as PD symptoms to cope with there are the side effects of those meds as well.

[DorieJordan12 in reply to Moodyblue]

,I waz diav

[redread]

You are fortunate that Sinamet works for you with no side effects. If that were the case with my husband, we would not be looking for something else. Also, LDN can take more time to be effective. Since it is a secondary use, we don't expect miracles but it is a low risk med, so people need to try.

[redread]

This is a serious discussion that is not helped by your ongoing diatribe. Please try to control your posts on this topic. Bordering on harassment