Is Parkinsons hereditary?: - Cure Parkinson's
Is Parkinsons hereditary?
i hope not, but it is a question the specialists always ask if there is any history in the family, i think my fathers mother was a sufferer
Oh my, Now that is the great debate and I truly wish I had an answer. My oponion is I think to some degree it is most defenitely. Or at least you need to be prdisposed to get it. My Mother had Parkinsons I have now have it. Two of her cousins had it also and one of my cousins has it too. From what I have researched they say that about 8% is linked to heredatary causes, but I could be wron. There are many ongoing studies to find the answer and maybe some day soon they will know. I hope this helps.
No one in my family has had PD before
We look for genetics among certain families and young onset parkinsons as there are families that have genetic links most from the Mediterranean areas. Lrkk2 prk2 but even if we find a genetic link at this time we don't have a neuro protector to prevent neurone break down . There is always the ethical question as to do you want to know if the risk is minute and you might never get it?
For many years the answer from most people would have been a resounding "No."
However it has become obvious in recent years that SOME people with Parkinson's have strong genetic predispositions toward developing the condition. Specific genes mean that the cell metabolism is unusual and, even under circumstances which would have no affect for most people, can result in cell damage and Parkinson's.
However, that isn't the end of it. It has been found, by analysing results of results (meta-analysis) that some genes show up more often in populations of people with Parkinson's than in others and that although they are not the cause of Parkinson's directly, they may make you more susceptible to lifestyle and environmental factors. The research into the protective effect of caffeine strongly suggested that for some genetic types caffeine had a good protection but for others it had no effect. .
More exciting than the actual result which shows that your Parkinson's may be slowed by caffeine is the indication that large scale drug trials should be taking into account the genetic background of the participants as the positive results in the people with the suitable genotypes would be swamped by the majority without. If it hadn't been for the genetic analysis of the caffeine results nobody would have spotted the positives linked to the prevalence of certain genes.
Let's turn the idea of genetic testing on its head. It is thought that Parkinson's is not inherited in the classical way that Huntingdon's or blue and brown eyes are. Rather, if you knew that you had a set of genes which makes you more likely to develop Parkinson's if you came into contact with sheep dip then you would have a clear choice surely. Wouldn't you want your children's career choices to be made on that basis rather than the pot luck they have now?
Another reason to support gene testing is the variability of people's responses to drugs. Everyday I read on here that what suits one person harms another. Wouldn't it be important to you to know at the outset which is which for your genes and circumstances? Quite a few years ago now a drug which had possible liver damage as a side effect was withdrawn from the market as the constant liver function tests and possible damage were thought to outweigh the relief some people got with its use. 'They' are now looking into the possibility that this might have been a genetic response and both the anti Parkinson's effect and the liver damage might be predicted from genome studies.
Sorry this is so long but I was at the World Parkinson's Congress in Glasgow when the caffeine results were announced and I can tell you, it certainly caused a stir there.
My husbands brother has it and I believe on looking back that their mother and grandfather had it , or at least many of the symptoms .. I am watching out now for some of the younger ones following .
i was diagnosed in 2002 with Parkinson's Disease. My sister, who lives in England,was diagnosed in 2010, I did not think that PD was hereditary. Other than being sister and brother, we grew up together in the suburbs of Long Island.
Look into 23andme.com.
People in the UK with siblings who have Parkinson's can take part in the Tracking Parkinson's study. parkinsons.org.uk/tracking Have a look at this link to the Parkinson's UK website.
I was diagnosed in 2011 and just had a DaT Scan to confirm it. NO ONE in my family has ever had, it to our knowledge. Of course, maybe it was just never diagnosed. Now I've been diagnosed with Stage 3 renal failure. Don't know if there's any connection but at 60yo I feel like I'm falling apart.
That's just "old age.......I feel like I'm falling apart sometimes too!
It would be so much easier if we just had "one" thing at a time to overcome.....but unfortunately pwp usually have at least 2 or more things that try our patients. Like arthritis, heart conditions, diabetes, scoliosis etc.....
You have to admit.....It's not boring! :o)
My husband thinks his grandfather had it.
Here's a PBS program which is excellent. Try to watch it more than once. There's a lot in there. Title: "My Father, My Brother, and I".
video.pbs.org/video/1082086...
I think My husband's PD might have something to do with his mother's health
and reproductive capacities. She endured several miscarriages and a
still birth. Then she had him. So maybe there was something
genetically 'off' in her body or her diet was not good or ?
Just speculating.
This webinar might give you some answers.
TOMORROW-TOMORROW-TOMORROW
28 June 2013 at 8 PM UK time
SPREAD THE WORD - PARKINSON'S MOVEMENT WEBINAR 6 "MEAN GENES "
The next Parkinson's Movement webinar is entitled MEAN GENES: THE GENETICS OF PARKINSON'S.
There ...TOMORROW-TOMORROW-TOMORROW
28 June 2013 at 8 PM UK time
SPREAD THE WORD - PARKINSON'S MOVEMENT WEBINAR 6 "MEAN GENES "
The next Parkinson's Movement webinar is entitled MEAN GENES: THE GENETICS OF PARKINSON'S.
There ...
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