I just started on Enbrel injections a little over a week ago. My first injection was on 12/20. I placed this injection in my abdomen. The only site reactions I had were a slight redness and itching (normal site reactions). My second injection was on 12/28 (working on getting my injections to the weekend & okayed by my provider). I place my second injection in my thigh. I noticed last night (12/30) that the injection site was slightly raised and reddened, and a little tender to firm touch. This morning (12/31) I noticed the size of the swelling and redness has increased and also noted a spotty raised red rash on my abdomen where my first injection was given. I know site injections can happen and are common, but when should I be concerned and notify my health care provider? Blessings for a prosperous and happy new year everyone.