Qing dai supplement: Anyone here... - Crohn's and Colit...

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Qing dai supplement

Crnalves profile image
3 Replies

Anyone here already tried to take Qing Dai supplement for UC? If so, let me know your experience please.

Thanks

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Crnalves profile image
Crnalves
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Graham49 profile image
Graham49

I haven't tried it but there are research papers on it, see below. Be careful, another paper reports a case of pulmonary arterial hypertension by someone using it. Best to discuss use with your doctor.

Clinical Efficacy and Safety of Oral Qing-Dai in Patients with Ulcerative Colitis: A Single-Center Open-Label Prospective Study

Sugimoto S.a · Naganuma M.a · Kiyohara H.a · Arai M.a · Ono K.a · Mori K.a · Saigusa K.a · Nanki K.a · Takeshita K.a · Takeshita T.a · Mutaguchi M.a · Mizuno S.a · Bessho R.a · Nakazato Y.b · Hisamatsu T.a · Inoue N.c · Ogata H.b · Iwao Y.c · Kanai T.a

Keywords: Inflammatory bowel diseaseUlcerative colitisUlcer healingColonChinese herbal medicineQing-DaiIndigo naturalisIndoleAryl hydrocarbon receptorInterleukin-22

Digestion 2016;93:193-201

doi.org/10.1159/000444217

Abstract

Background/Aims: Chinese herbal medicine Qing-Dai (also known as indigo naturalis) has been used to treat various inflammatory conditions. However, not much has been studied about the use of oral Qing-Dai in the treatment for ulcerative colitis (UC) patients. Studies exploring alternative treatments for UC are of considerable interest. In this study, we aimed at prospectively evaluating the safety and efficacy of Qing-Dai for UC patients. Methods: The open-label, prospective pilot study was conducted at Keio University Hospital. A total of 20 patients with moderate UC activity were enrolled. Oral Qing-Dai in capsule form was taken twice a day (daily dose, 2 g) for 8 weeks. Results: At week 8, the rates of clinical response, clinical remission, and mucosal healing were 72, 33, and 61%, respectively. The clinical and endoscopic scores, CRP levels, and fecal occult blood results were also significantly improved. We observed 2 patients with mild liver dysfunction; 1 patient discontinued due to infectious colitis and 1 patient discontinued due to mild nausea. Conclusion: This is the first prospective study indicating that oral Qing-Dai is effective for inducing remission in patients with moderate UC activity and can be tolerated. Thus, Qing-Dai may be considered an alternative treatment for patients, although further investigation is warranted.

Crnalves profile image
Crnalves in reply to Graham49

Thanks for replying and sharing this study. We read that one and also others, and my boyfriend decided to take it, he started almost a week ago, 1g a day. For now he's feeling ok, I hope it works!

alfreddy7 profile image
alfreddy7 in reply to Crnalves

Hi,

I know this is an old post. I was wondering how your boyfriend is doing with the Qing Dai?

I’ve been taking it for about 3 years I would say. But it’s on and off.

I pretty much take it when my UC is really bad.

I hope he’s going much better now.