Antineoplastons

[Floydpup]

Hello all. I recently came across information regarding Dr Stanislaw Burzynski and his "successful" treatment of cancer patients by use of Neoplastons. Is anybody familiar with this? Is this worthy of pursuit or is it debunked? Thank you for your input.FP

[scryer99]

Sloan Kettering does not seem overly enthusiastic:

mskcc.org/cancer-care/integ...

I see a long list of side effects and not a lot of scientific-based study proof of efficacy. I'd steer clear of it myself.

[Floydpup in reply to scryer99]

Thanks for the link scryer99.

[AussieNeil Administrator]

A few extracts from Wikipedia: en.wikipedia.org/wiki/Burzy... might explain why it's considered debunked.

Although the therapy is promoted as natural and benign, it is in reality a form of chemotherapy with harmful side effects including severe neurotoxicity.[1]

Clinical trials

According to the National Cancer Institute, as of April 2013, "no phase III randomized, controlled trials of antineoplastons as a treatment for cancer have been conducted. Publications have taken the form of case reports, phase I clinical trials, toxicity studies, and phase II clinical trials",[26] and "for the most part, these publications have been authored by the developer of the therapy, Dr. Burzynski, in conjunction with his associates at the Burzynski Clinic. Although these studies often report remissions, other investigators have not been successful in duplicating these results."[27]

Efficacy

Although Burzynski and his associates claim success in the use of antineoplaston combinations for the treatment of various diseases, and some of the clinic's patients say they have been helped,[33] there is no clinical evidence of the efficacy of these methods. The consensus among the professional community, as represented by the American Cancer Society[33] and Cancer Research UK[34] is that antineoplaston therapy is unproven and the overall probability of the treatment turning out to be as claimed is low due to lack of credible mechanisms and the poor state of research after more than 35 years of investigation.

:

There is no convincing evidence from randomized controlled trials in the scientific literature that antineoplastons are useful treatments of cancer, and the U.S. Food and Drug Administration (FDA) has not approved these products for the treatment of any disease.[36] The American Cancer Society has stated since 1983 that there is no evidence that antineoplastons have any beneficial effects in cancer and recommended that people not buy these products since there could be serious health consequences.[33][37] A 2004 medical review described antineoplaston treatment as a "disproven therapy".[10]

Neil

[Floydpup in reply to AussieNeil]

Thanks Neil.

[Kwenda]

See also Cancer Research UK, which urges extreme caution.

cancerresearchuk.org/about-...

Dick

[Floydpup in reply to Kwenda]

Thanks Kwenda.